Piritramide

Piritramide

SCHEMBL26151

N#CC(CCN1CCC(C(N)=O)(N2CCCCC2)CC1)(c1ccccc1)c1ccccc1

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNA3 P22001 9/20 0.64
TSHR P16473 1/20 0.58
OPRM1 P35372 2/20 0.54
CCR1 P32246 2/20 0.53
RAB9A P51151 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
CHRM2 P08172 1/20 0.52
HTR1A P08908 1/20 0.52
ADRA2A P08913 1/20 0.52
CHRM1 P11229 1/20 0.52
DRD1 P21728 1/20 0.52
TBXA2R P21731 1/20 0.52
SLC6A2 P23975 1/20 0.52
SLC6A4 P31645 1/20 0.52
ADRA1A P35348 1/20 0.52
DRD3 P35462 1/20 0.52
SLC6A3 Q01959 1/20 0.52
KCNH2 Q12809 1/20 0.52
HRH3 Q9Y5N1 1/20 0.52
ALDH1A1 P00352 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Piritramide SCHEMBL5399631 0.94 KCNA3 (0.57) KCNA3TSHROPRM1CCR1RAB9A
Piritramide SCHEMBL13723412 0.83 KCNA3 (0.44) KCNA3TSHROPRM1CCR1RAB9A
Piritramide SCHEMBL5886171 0.80 OPRM1 (0.67) KCNA3OPRM1LMNA
SCHEMBL11625051 0.79 KCNA3 (1.00) KCNA3OPRM1CCR1RAB9ANPSR1
Piritramide SCHEMBL28086563 0.79 OPRM1 (0.55) KCNA3TSHROPRM1CCR1RAB9A
Hydrochloric Acid SCHEMBL11628063 0.77 KCNA3 (0.94) KCNA3OPRM1CCR1RAB9ANPSR1
Difenoxin SCHEMBL123801 0.76 KCNA3 (0.78) KCNA3OPRM1CCR1RAB9ANPSR1
Difenoxin SCHEMBL11604884 0.75 KCNA3 (0.76) KCNA3OPRM1CCR1RAB9ANPSR1
Difenoxin SCHEMBL149008 0.75 KCNA3 (0.76) KCNA3OPRM1CCR1RAB9ANPSR1
SCHEMBL10064332 0.74 KCNA3 (0.78) KCNA3OPRM1CCR1RAB9ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 9077 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4255391-B1 LUMINOL FOR USE IN THE TREATMENT OF SEQUELAE OF A SARS-COV-2 INFECTION METRIOPHARM AG (CH) 2026-05-06 EP claimed
EP-4724049-A1 MODIFIED RELEASE FILL COMPOSITIONS FOR DOSAGE FORMS AND METHODS OF PREPARATION AND USE THEREOF Catalent Ontario Limited (CA) 2026-04-15 EP claimed
US-20250319074-A1 TREATMENT AND MANAGEMENT OF AUGMENTATION IN RESTLESS LEGS SYNDROME UNIV EAST CAROLINA (US) 2025-10-16 US claimed
US-20250255781-A1 PROCESSES FOR PREPARATION OF 3-D PRINTED PHARMACEUTICAL PRODUCTS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-08-14 US claimed
US-12383743-B2 Treatment of addiction and dependency TACA JR ARTURO C (US) 2025-08-12 US claimed
US-20250228771-A1 ALKALINE INTRAORAL PRODUCTS EMPLICURE AB (publ) (SE) 2025-07-17 US claimed
EP-4581017-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS Biodol Therapeutics (FR) 2025-07-09 EP claimed
EP-4565202-A1 ALKALINE INTRAORAL PRODUCTS EMPLICURE AB (publ) (SE) 2025-06-11 EP claimed
US-12296043-B2 Liquisoft capsules PATHEON SOFTGELS INC. (US) 2025-05-13 US claimed
WO-2024226905-A9 METHOD FOR PREVENTING ADDICTION TO THERAPEUTIC OPIOIDS RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2025-04-03 WO claimed
US-5654281-A Inhibiting the development of tolerance to and/or dependence on an addictive substance VIRGINIA COMMONWEALTH UNIVERSITY (US) 1997-08-05 US claimed
EP-0785775-A1 MELT-EXTRUDED ORALLY ADMINISTRABLE OPIOID FORMULATIONS Euroceltique S.A. (LU) 1997-07-30 EP claimed
EP-0731694-A4 1996-10-02 EP claimed
EP-0731694-A1 OPIOID FORMULATIONS FOR TREATING PAIN Euroceltique S.A. (LU) 1996-09-18 EP claimed
CN-1130352-A Method for relieving pain by orally administering 24-hour sustained-release opioid dosage form capable of rapidly increasing initial blood concentration of patient EURO CELTIQUE SA (LU) 1996-09-04 CN claimed
WO-1996014058-A1 MELT-EXTRUDED ORALLY ADMINISTRABLE OPIOID FORMULATIONS EURO-CELTIQUE, S.A. (LU) 1996-05-17 WO claimed
WO-1995014460-A1 OPIOID FORMULATIONS FOR TREATING PAIN EURO-CELTIQUE S.A. (LU) 1995-06-01 WO claimed
EP-0647448-A1 Orally administrable opioid formulations having extended duration of effect Euroceltique S.A. (LU) 1995-04-12 EP claimed
EP-0608893-A1 Inhibiting the development of tolerance to and/or dependence on an additive substance VIRGINIA COMMONWEALTH UNIVERSITY (US) 1994-08-03 EP claimed
US-4126684-A 4-AMINO-3-P-HALOPHENYLBUTYRIC ACIDS AND THEIR DERIVATIVES USED IN THE CONTROL OF NARCOTIC ABUSE CIBA-GEIGY CORPORATION (US) 1978-11-21 US claimed