Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.72 |
| ▸ | MAPT | P10636 | 1/20 | 0.72 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.72 |
| ▸ | BLM | P54132 | 1/20 | 0.72 |
| ▸ | PDE5A | O76074 | 2/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SCN4A | P35499 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19512822 | 0.90 | KDM4E (0.72) | MEN1KMT2AKDM4EALDH1A1CYP3A4 | |
| Oxcarbazepine SCHEMBL29433241 | 0.84 | KDM4E (1.00) | MEN1KMT2AKDM4EALDH1A1CYP3A4 | |
| Oxcarbazepine SCHEMBL29359799 | 0.84 | KDM4E (1.00) | MEN1KMT2AKDM4EALDH1A1CYP3A4 | |
| Oxcarbazepine SCHEMBL4655725 | 0.84 | KDM4E (1.00) | MEN1KMT2AKDM4EALDH1A1CYP3A4 | |
| Oxcarbazepine SCHEMBL35129 | 0.84 | KDM4E (1.00) | MEN1KMT2AKDM4EALDH1A1CYP3A4 | |
| SCHEMBL2615541 | 0.84 | MEN1 (0.72) | MEN1KMT2AKDM4EALDH1A1CYP3A4 | |
| Oxcarbazepine SCHEMBL17372732 | 0.83 | KDM4E (0.97) | MEN1KMT2AKDM4EALDH1A1CYP3A4 | |
| Oxcarbazepine SCHEMBL27944289 | 0.83 | KDM4E (0.97) | MEN1KMT2AKDM4EALDH1A1CYP3A4 | |
| Oxcarbazepine SCHEMBL29123953 | 0.82 | ALDH1A1 (0.89) | MEN1KMT2AKDM4EALDH1A1CYP3A4 | |
| Oxcarbazepine SCHEMBL2885435 | 0.80 | KDM4E (0.89) | MEN1KMT2AKDM4EALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120095217-A1 | FLUORINE CONTAINING COMPOUNDS AND METHODS OF USE THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095217-A1 | FLUORINE CONTAINING COMPOUNDS AND METHODS OF USE THEREOF | FLI1, CDC73, FOS | MEN1 81/4885KMT2A 1417/4885KDM4E 2391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.