Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2615376 | 1.00 | HTR1A (0.61) | HTR1ASIGMAR1KDM4ECYP1A2GAA | |
| SCHEMBL7521159 | 0.79 | SIGMAR1 (0.66) | HTR1ASIGMAR1KDM4ECYP1A2GAA | |
| SCHEMBL30350966 | 0.76 | SIGMAR1 (0.66) | HTR1ASIGMAR1KDM4ECYP1A2GAA | |
| SCHEMBL10911831 | 0.76 | HTR1A (1.00) | HTR1ASIGMAR1KDM4ECYP1A2CYP2C9 | |
| SCHEMBL9672260 | 0.76 | HTR1A (0.59) | HTR1ASIGMAR1 | |
| SCHEMBL9766008 | 0.75 | SIGMAR1 (0.60) | HTR1ASIGMAR1KDM4ECYP1A2GAA | |
| SCHEMBL9671074 | 0.75 | HTR1A (0.58) | HTR1ASIGMAR1 | |
| SCHEMBL13532482 | 0.75 | HTR1A (1.00) | HTR1ASIGMAR1KDM4ECYP1A2CYP2C9 | |
| SCHEMBL7991554 | 0.75 | HTR1A (0.60) | HTR1ASIGMAR1 | |
| SCHEMBL7855443 | 0.75 | SIGMAR1 (0.63) | HTR1ASIGMAR1KDM4ECYP1A2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120095217-A1 | FLUORINE CONTAINING COMPOUNDS AND METHODS OF USE THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095217-A1 | FLUORINE CONTAINING COMPOUNDS AND METHODS OF USE THEREOF | FLI1, CDC73, FOS | HTR1A 3795/4885SIGMAR1 1165/4885KDM4E 2391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.