Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.40 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ESR1 | P03372 | 4/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13284589 | 0.82 | PPARA (0.64) | PPARATSHRSMN1; SMN2TTRCYP1A2 | |
| SCHEMBL29840766 | 0.82 | PPARA (0.64) | PPARATSHRSMN1; SMN2TTRCYP1A2 | |
| SCHEMBL90173 | 0.79 | LMNA (0.39) | TSHRTDP1KDM4ELMNAHTT | |
| SCHEMBL22138650 | 0.75 | MRGPRX4 (0.47) | PPARATSHRSMN1; SMN2TTRCYP1A2 | |
| SCHEMBL21757404 | 0.74 | PPARA (0.43) | PPARATSHRSMN1; SMN2TTRCYP1A2 | |
| SCHEMBL12203843 | 0.74 | TSHR (0.68) | PPARATSHRSMN1; SMN2TTRCYP1A2 | |
| SCHEMBL19123074 | 0.74 | HTT (0.45) | TSHRCYP1A2TDP1KDM4EESR1 | |
| SCHEMBL10202960 | 0.71 | L3MBTL1 (0.61) | SMN1; SMN2TTRCYP1A2CYP2C9TDP1 | |
| SCHEMBL15367027 | 0.70 | TSHR (0.38) | PPARATSHRSMN1; SMN2TTRCYP1A2 | |
| SCHEMBL16705082 | 0.69 | CYP1A2 (0.39) | SMN1; SMN2CYP1A2CYP2C9TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120095217-A1 | FLUORINE CONTAINING COMPOUNDS AND METHODS OF USE THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095217-A1 | FLUORINE CONTAINING COMPOUNDS AND METHODS OF USE THEREOF | FLI1, CDC73, FOS | PPARA 1435/4885TSHR 784/4885SMN1; SMN2 888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.