SCHEMBL2615674

SCHEMBL2615674

COc1nc(OC)nc(C(=O)c2cccc(Cl)c2NS(=O)(=O)C(F)F)n1

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CCR9 P51686 1/20 0.39
CCR4 P51679 5/20 0.35
ITGB1 P05556 2/20 0.34
ITGA4 P13612 2/20 0.34
MLKL Q8NB16 1/20 0.33
KMT2A Q03164 3/20 0.32
MAPK10 P53779 1/20 0.32
MAPT P10636 2/20 0.32
MEN1 O00255 1/20 0.32
KEAP1 Q14145 1/20 0.32
NFE2L2 Q16236 1/20 0.32
P2RY1 P47900 1/20 0.32
F2 P00734 1/20 0.31
HPGD P15428 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13168812 0.94 CCR9 (0.36) CCR9CCR4MLKL
SCHEMBL19034695 0.91 CCR9 (0.35) CCR9CCR4MLKLF2
SCHEMBL13044431 0.88 NPSR1 (0.39) CCR9MLKLMAPK10SMN1; SMN2
SCHEMBL2615681 0.88 NPC1 (0.37) ITGB1ITGA4MLKLKMT2AMAPT
SCHEMBL13936700 0.88 MLKL (0.33) MLKLMAPT
SCHEMBL10068049 0.88 RXFP1 (0.36) MLKLHPGDSMN1; SMN2
SCHEMBL3826176 0.87 MLKL (0.35) MLKL
SCHEMBL3834184 0.87 MLKL (0.33) MLKLKMT2AMAPTMEN1F2
SCHEMBL3805420 0.86 SMN1; SMN2 (0.39) CCR9CCR4MLKLMAPK10MAPT
SCHEMBL13498410 0.84 CCR9 (0.39) CCR9CCR4ITGB1ITGA4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023031117-A1 PERFORMANCE GAIN IN ALS INHIBITOR HERBICIDE TOLERANT BETA VULGARIS PLANTS BY COMBINATION OF BEST FITTING ALS LARGE AND SMALL SUBUNITS BAYER AKTIENGESELLSCHAFT (DE) 2023-03-09 WO disclosed
WO-2023031112-A1 ALS-INHIBITOR HERBICIDE TOLERANT BETA VULGARIS HYBRIDS WITH INCREASED HETEROSIS BAYER AKTIENGESELLSCHAFT (DE) 2023-03-09 WO disclosed
US-11371057-B2 Methods of using ALS inhibitor herbicides for control of unwanted vegetation in ALS inhibitor herbicide tolerant beta vulgaris plants BAYER INTELLECTUAL PROPERTY GMBH (DE) 2022-06-28 US disclosed
EP-2931034-B2 USE OF ALS INHIBITOR HERBICIDES FOR CONTROL OF UNWANTED VEGETATION IN ALS INHIBITOR HERBICIDE TOLERANT BETA VULGARIS PLANTS BAYER CROPSCIENCE AG (DE) 2022-04-27 EP disclosed
EP-3284346-B1 USE OF ALS INHIBITOR HERBICIDES FOR CONTROL OF UNWANTED VEGETATION IN ALS INHIBITOR HERBICIDE TOLERANT BETA VULGARIS PLANTS BAYER CROPSCIENCE AG (DE) 2021-07-07 EP disclosed
EP-3036331-B1 ALS INHIBITOR HERBICIDE TOLERANT MUTANT PLANTS BASF Agricultural Solutions Seed US LLC (US) 2021-06-16 EP disclosed
US-20200095602-A1 METHODS OF USING ALS INHIBITOR HERBICIDES FOR CONTROL OF UNWANTED VEGETATION IN ALS INHIBITOR HERBICIDE TOLERANT BETA VULGARIS PLANTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2020-03-26 US disclosed
US-10544426-B2 Methods of using ALS inhibitor herbicides for control of unwanted vegetation in ALS inhibitor herbicide tolerant beta vulgaris plants BAYER INTELLECTUAL PROPERTY GMBH (DE) 2020-01-28 US disclosed
US-20190136254-A1 ALS Inhibitor Herbicide Tolerant Mutant Plants BAYER CROPSCIENCE LP 2019-05-09 US disclosed
EP-2931034-B1 USE OF ALS INHIBITOR HERBICIDES FOR CONTROL OF UNWANTED VEGETATION IN ALS INHIBITOR HERBICIDE TOLERANT BETA VULGARIS PLANTS BAYER CROPSCIENCE AG (DE) 2018-06-13 EP disclosed
WO-2010017928-A1 HERBICIDAL COMBINATION COMPRISING DIMETHOXY-TRIAZINYL-SUBSTITUTED DIFLUOROMETHANE SULFONYANILIDES BAYER CROPSCIENCE AG (DE) 2010-02-18 WO disclosed
WO-2010017923-A2 HERBICIDAL COMBINATION WITH DIMETHOXY-TRIAZINYL-SUBSTITUTED DIFLUOROMETHANE SULFONYLANILIDES BAYER CROPSCIENCE AG (DE) 2010-02-18 WO disclosed
WO-2010017929-A1 HERBICIDAL COMBINATION COMPRISING DIMETHOXYTRIAZINYL-SUBSTITUTED DIFLUOROMETHANE SULFONYLANILIDES BAYER CROPSCIENCE AG (DE) 2010-02-18 WO disclosed
WO-2010017925-A2 HERBICIDAL-SAFENER-COMBINATION COMPRISING DIMETHOXYTRIAZINYL- SUBSTITUTED DIFLUORMETHANE SULFONYLANILIDES BAYER CROPSCIENCE AG (DE) 2010-02-18 WO disclosed
WO-2010017927-A2 HERBICIDAL COMBINATION COMRPISING DIMETHOXYTRIAZINYL-SUBSTITUTED DIFLUOROMETHANE SULFONYLANILIDES BAYER CROPSCIENCE AG (DE) 2010-02-18 WO disclosed
WO-2010017926-A2 HERBICIDAL COMBINATION COMPRISING DIMETHOXY-TRIAZINYL-SUBSTITUTED DIFLUOROMETHANE SULFONYLANILIDES BAYER CROPSCIENCE AG (DE) 2010-02-18 WO disclosed
WO-2010017930-A2 HERBICIDAL COMBINATION COMPRISING DIMETHOXY-TRIAZINYL-SUBSTITUTED DIFLUOROMETHANE SULFONYLANILIDES BAYER CROPSCIENCE AG (DE) 2010-02-18 WO disclosed
WO-2010017931-A2 HERBICIDAL COMBINATION COMPRISING DIMETHOXY-TRIAZINYL-SUBSTITUTED DIFLUOROMETHANE SULFONYLANILIDES BAYER CROPSCIENCE AG (DE) 2010-02-18 WO disclosed
WO-2010017921-A2 HERBICIDAL COMBINATION COMPRISING DIMETHOXY-TRIAZINYL-SUBSTITUTED DIFLUOROMETHANE SULFONYLANILIDES BAYER CROPSCIENCE AG (DE) 2010-02-18 WO disclosed
WO-2010017922-A2 HERBICIDAL COMBINATION COMPRISING DIMETHOXY-TRIAZINYL-SUBSTITUTED DIFLUOROMETHANE SULFONYLANILIDES BAYER CROPSCIENCE AG (DE) 2010-02-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200095602-A1 METHODS OF USING ALS INHIBITOR HERBICIDES FOR CONTROL OF UNWANTED VEGETATION IN ALS INHIBITOR HERBICIDE TOLERANT BETA VULGARIS PLANTS LCT, HTT, GLO1 CCR9 3730/4885CCR4 3232/4885ITGB1 4862/4885
US-20190136254-A1 ALS Inhibitor Herbicide Tolerant Mutant Plants HACL2, LCT, CAT CCR9 4655/4885CCR4 4554/4885ITGB1 4880/4885
US-11371057-B2 Methods of using ALS inhibitor herbicides for control of unwanted vegetation in ALS inhibitor herbicide tolerant beta vulgaris plants LCT, HTT, GLO1 CCR9 3730/4885CCR4 3232/4885ITGB1 4862/4885
US-10544426-B2 Methods of using ALS inhibitor herbicides for control of unwanted vegetation in ALS inhibitor herbicide tolerant beta vulgaris plants LCT, HTT, GLO1 CCR9 3730/4885CCR4 3232/4885ITGB1 4862/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.