Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 7/20 | 0.31 |
| ▸ | CDK9 | P50750 | 7/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26157228 | 0.79 | KDM4E (0.36) | LMNATSHRALDH1A1 | |
| SCHEMBL25109036 | 0.77 | FGFR1 (0.31) | — | |
| SCHEMBL25109488 | 0.77 | FGFR1 (0.31) | — | |
| SCHEMBL26157093 | 0.76 | BACE1 (0.33) | — | |
| SCHEMBL16803086 | 0.75 | CYP3A4 (0.40) | ALDH1A1 | |
| SCHEMBL16803140 | 0.75 | LMNA (0.37) | LMNATSHRTRPA1CCNT1CDK9 | |
| SCHEMBL25627787 | 0.71 | CDK9 (0.39) | CCNT1CDK9 | |
| SCHEMBL1783157 | 0.71 | LMNA (0.66) | LMNATSHRTRPA1ALOX15CYP1B1 | |
| SCHEMBL15450107 | 0.71 | LMNA (0.66) | LMNATSHRTRPA1ALOX15CYP1B1 | |
| SCHEMBL12909964 | 0.71 | LMNA (0.66) | LMNATSHRTRPA1ALOX15CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023093728-A1 | BRM SELECTIVE DEGRADATION AGENT COMPOUND AND USE THEREOF | 江苏先声药业有限公司 | 2023-06-01 | — | — | WO | disclosed |