Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CKS1B | P61024 | 1/20 | 0.32 |
| ▸ | SKP1 | P63208 | 1/20 | 0.32 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26157092 | 0.83 | ALDH1A1 (0.37) | KDM4EKMT2AALDH1A1TSHRHPGD | |
| SCHEMBL26157227 | 0.80 | ALDH1A1 (0.33) | KMT2AALDH1A1TSHRHPGDPKM | |
| SCHEMBL26157240 | 0.79 | LMNA (0.36) | ALDH1A1TSHRLMNA | |
| SCHEMBL25109036 | 0.76 | FGFR1 (0.31) | — | |
| SCHEMBL25109488 | 0.76 | FGFR1 (0.31) | — | |
| SCHEMBL26157094 | 0.74 | ACACB (0.43) | KDM4ECYP2C19KMT2AALDH1A1TSHR | |
| SCHEMBL24461253 | 0.74 | ACACB (0.43) | KDM4ECYP2C19KMT2AALDH1A1TSHR | |
| SCHEMBL12525598 | 0.71 | NPC1 (0.45) | KDM4ECYP2C19KMT2AALDH1A1TSHR | |
| SCHEMBL26157319 | 0.71 | ADRA1A (0.52) | KDM4ECYP2C19KMT2AALDH1A1TSHR | |
| SCHEMBL20152894 | 0.68 | KDM4E (0.50) | KDM4ECYP2C19RIPK1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023093728-A1 | BRM SELECTIVE DEGRADATION AGENT COMPOUND AND USE THEREOF | 江苏先声药业有限公司 | 2023-06-01 | — | — | WO | disclosed |