Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | OGA | O60502 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26157317 | 0.82 | KMT2A (0.50) | KMT2AMEN1TSHROGA | |
| SCHEMBL30635452 | 0.80 | HRH3 (0.52) | KMT2AMEN1HRH3 | |
| SCHEMBL12036196 | 0.79 | KDM4E (0.46) | KMT2AMEN1SMN1; SMN2TP53 | |
| SCHEMBL20425044 | 0.77 | KDM4E (0.48) | POLBCHRM4 | |
| SCHEMBL30635456 | 0.76 | HRH3 (0.47) | KMT2AMEN1POLBHRH3 | |
| SCHEMBL25482532 | 0.75 | KMT2A (0.39) | KMT2AMEN1TSHRCHRM4HRH3 | |
| SCHEMBL26157318 | 0.74 | ACHE (0.53) | KMT2AMEN1TSHRCHRM4HRH3 | |
| SCHEMBL20152894 | 0.74 | KDM4E (0.50) | KMT2AMEN1SMN1; SMN2POLBMAPT | |
| SCHEMBL30635458 | 0.74 | HRH3 (0.54) | TSHRSMN1; SMN2POLBHRH3 | |
| SCHEMBL20152891 | 0.73 | RIPK1 (0.53) | TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023093728-A1 | BRM SELECTIVE DEGRADATION AGENT COMPOUND AND USE THEREOF | 江苏先声药业有限公司 | 2023-06-01 | — | — | WO | disclosed |