Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.55 |
| ▸ | PPARG | P37231 | 2/20 | 0.53 |
| ▸ | MME | P08473 | 5/20 | 0.52 |
| ▸ | ACE | P12821 | 4/20 | 0.52 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.52 |
| ▸ | CPA1 | P15085 | 3/20 | 0.52 |
| ▸ | CTSS | P25774 | 1/20 | 0.52 |
| ▸ | CTSK | P43235 | 1/20 | 0.52 |
| ▸ | PAM | P19021 | 1/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.52 |
| ▸ | GNPAT | O15228 | 1/20 | 0.52 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.52 |
| ▸ | ITGAV | P06756 | 1/20 | 0.52 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.52 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10626666 | 1.00 | LMNA (0.56) | LMNAPTPN1PPARGMMEACE | |
| SCHEMBL10622597 | 1.00 | LMNA (0.56) | LMNAPTPN1PPARGMMEACE | |
| Afalanine SCHEMBL8587729 | 0.87 | CTSS (0.65) | LMNAMMEACEACE2CPA1 | |
| Afalanine SCHEMBL331330 | 0.87 | CTSS (0.65) | LMNAMMEACEACE2CPA1 | |
| Afalanine SCHEMBL158612 | 0.87 | CTSS (0.65) | LMNAMMEACEACE2CPA1 | |
| Afalanine SCHEMBL158613 | 0.87 | CTSS (0.65) | LMNAMMEACEACE2CPA1 | |
| SCHEMBL10626692 | 0.87 | FOLH1 (0.56) | ACECTSSCTSKPAMITGB3 | |
| SCHEMBL10622096 | 0.87 | FOLH1 (0.56) | ACECTSSCTSKPAMITGB3 | |
| SCHEMBL10626696 | 0.87 | FOLH1 (0.56) | ACECTSSCTSKPAMITGB3 | |
| SCHEMBL6436289 | 0.86 | MME (0.68) | LMNAMMEACEACE2CPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3500252-B1 | MODIFIED PEPTIDES FOR USE IN TREATING NEURODEGENERATIVE DISORDERS | NEURO BIO LTD (GB) | 2022-11-02 | — | — | EP | disclosed |
| US-20210094983-A1 | MODIFIED PEPTIDES FOR USE IN TREATING NEURODEGENERATIVE DISORDERS | NEURO-BIO LTD. (GB) | 2021-04-01 | — | — | US | disclosed |
| US-9440988-B2 | Regulators of the hedgehog pathway, compositions and uses related thereto | JOHN HOPKINS UNIVERSITY SCHOOL OF MEDICINE (US) | 2016-09-13 | — | — | US | disclosed |
| US-20120135066-A1 | REGULATORS OF THE HEDGEHOG PATHWAY, COMPOSITIONS AND USES RELATED THERETO | BEACHY PHILIP A (US) | 2012-05-31 | — | — | US | disclosed |
| US-8163719-B2 | Regulators of the hedgehog pathway, compositions and uses related thereto | JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE (US) | 2012-04-24 | — | — | US | disclosed |
| US-20110263519-A1 | REGULATORS OF THE HEDGEHOG PATHWAY, COMPOSITIONS AND USES RELATED THERETO | JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE (US) | 2011-10-27 | — | — | US | disclosed |
| US-4762881-A | Photoreactive benzoylphenylalanines and related peptides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120135066-A1 | REGULATORS OF THE HEDGEHOG PATHWAY, COMPOSITIONS AND USES RELATED THERETO | SHH, GLI1, SMO | LMNA 3470/4885PTPN1 1986/4885PPARG 2384/4885 |
| US-20210094983-A1 | MODIFIED PEPTIDES FOR USE IN TREATING NEURODEGENERATIVE DISORDERS | IAPP, NLN, APP | LMNA 2569/4885PTPN1 3363/4885PPARG 2955/4885 |
| US-20110263519-A1 | REGULATORS OF THE HEDGEHOG PATHWAY, COMPOSITIONS AND USES RELATED THERETO | SHH, GLI1, SMO | LMNA 3470/4885PTPN1 1986/4885PPARG 2384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.