Sugi Predict

Sugi Predict / Compounds / SCHEMBL26164131

SCHEMBL26164131

SCHEMBL26164131

Ic1cncn1-c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ HTT P42858 1/20 0.44
▸ FGFR1 P11362 3/20 0.42
▸ HSP90AA1 P07900 1/20 0.40
▸ HSP90AB1 P08238 1/20 0.40
▸ NOS1 P29475 3/20 0.39
▸ CYP3A4 P08684 1/20 0.38
▸ RAB9A P51151 1/20 0.37
▸ SRC P12931 1/20 0.34
▸ ALDH1A1 P00352 1/20 0.34
▸ TDP1 Q9NUW8 1/20 0.34
▸ GABRA5 P31644 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5172891 0.74 HSP90AA1 (0.46) HTTFGFR1HSP90AA1HSP90AB1NOS1
SCHEMBL9771328 0.74 FGFR1 (0.42) HTTFGFR1HSP90AA1HSP90AB1NOS1
SCHEMBL3272205 0.74 CYP3A4 (0.53) HTTFGFR1HSP90AA1HSP90AB1NOS1
SCHEMBL544333 0.74 NOS1 (0.42) HTTFGFR1HSP90AA1HSP90AB1NOS1
SCHEMBL12676747 0.72 CYP11B1 (0.50) HTTFGFR1HSP90AA1HSP90AB1CYP3A4
SCHEMBL20033972 0.71 HSP90AA1 (0.51) HTTFGFR1HSP90AA1HSP90AB1NOS1
SCHEMBL10183098 0.71 HSP90AA1 (0.41) HTTFGFR1HSP90AA1HSP90AB1NOS1
SCHEMBL2359179 0.69 NOS1 (0.52) HTTFGFR1HSP90AA1HSP90AB1NOS1
SCHEMBL7563960 0.69 ATM (0.53) HTTFGFR1HSP90AA1HSP90AB1NOS1
SCHEMBL5383780 0.69 HSP90AA1 (0.40) HTTFGFR1HSP90AA1HSP90AB1NOS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122029158-A EGFR inhibitors 缆图药品公司 2026-05-12 — — CN disclosed
US-12610732-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2026-04-21 — — US disclosed
US-12497420-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2025-12-16 — — US disclosed
EP-4358685-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2025-12-03 — — EP disclosed
EP-4650415-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2025-11-19 — — EP disclosed
EP-4584259-A1 CK1ALPHA AND DUAL CK1ALPHA / GSPT1 DEGRADING COMPOUNDS Innovo Therapeutics, Inc. (US) 2025-07-16 — — EP disclosed
WO-2025080784-A1 EGFR INHIBITORS BLUEPRINT MEDICINES CORPORATION (US) 2025-04-17 — — WO disclosed
US-20240199603-A1 HPK1 ANTAGONISTS AND USES THEREOF SCHRÖDINGER, INC. 2024-06-20 — — US disclosed
US-20240158370-A1 CK1 alpha AND DUAL CK1 alpha / GSPT1 DEGRADING COMPOUNDS INNOVO THERAPEUTICS, INC. 2024-05-16 — — US disclosed
EP-4358685-A2 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2024-04-24 — — EP disclosed
US-11926625-B2 HPK1 antagonists and uses thereof Nimbus Saturn, Inc. (US) 2024-03-12 — — US disclosed
WO-2024029583-A1 NOVEL PYRAZOLE DERIVATIVE AND USE OF SAME 国立研究開発法人理化学研究所 2024-02-08 — — WO disclosed
US-20230167145-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-06-01 — — US disclosed
US-20230167145-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-06-01 — — US disclosed
US-20230167145-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-06-01 — — US disclosed
US-20230117631-A1 HPK1 ANTAGONISTS AND USES THEREOF Nimbus Saturn, Inc. 2023-04-20 — — US disclosed
US-20230115552-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-04-13 — — US disclosed
CN-114380867-A Organic electroluminescent material and device 环球展览公司 2022-04-22 — — CN disclosed
US-20220112232-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-04-14 — — US disclosed
EP-3978583-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2022-04-06 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240199603-A1 HPK1 ANTAGONISTS AND USES THEREOF PDXK, HIPK1, PCK1 HTT 1147/4885FGFR1 3115/4885HSP90AA1 755/4885
US-20230117631-A1 HPK1 ANTAGONISTS AND USES THEREOF PDXK, HIPK1, PCK1 HTT 1147/4885FGFR1 3115/4885HSP90AA1 755/4885
US-20220112232-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OR10J3 HTT 2044/4885FGFR1 4344/4885HSP90AA1 4542/4885
US-20240158370-A1 CK1 alpha AND DUAL CK1 alpha / GSPT1 DEGRADING COMPOUNDS CKS1B, CKS2, MARK1 HTT 2755/4885FGFR1 260/4885HSP90AA1 1477/4885
US-20230115552-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OSBP HTT 2047/4885FGFR1 4087/4885HSP90AA1 4263/4885
US-12610732-B2 Organic electroluminescent materials and devices ICOSLG, SSB, SART3 HTT 3103/4885FGFR1 2574/4885HSP90AA1 4254/4885
US-20230167145-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OSBP HTT 2047/4885FGFR1 4087/4885HSP90AA1 4263/4885
US-12497420-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, OR10J3 HTT 2044/4885FGFR1 4344/4885HSP90AA1 4542/4885
US-11926625-B2 HPK1 antagonists and uses thereof PDXK, HIPK1, PCK1 HTT 1147/4885FGFR1 3115/4885HSP90AA1 755/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.