SCHEMBL26164381

SCHEMBL26164381

c1ccc(-c2ccc3c(c2)Oc2ccc(-c4nc(-c5ccccc5)nc(-c5ccc6c(c5)oc5ccccc56)n4)c4cccc-3c24)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP12 P39900 1/20 0.34
MMP13 P45452 1/20 0.34
PLA2G2A P14555 3/20 0.33
PLA2G4A P47712 3/20 0.33
HCRTR1 O43613 1/20 0.33
PLA2G10 O15496 1/20 0.32
KDM4E B2RXH2 3/20 0.32
ATM Q13315 3/20 0.32
MAPK1 P28482 2/20 0.32
HSD17B10 Q99714 2/20 0.32
USP2 O75604 1/20 0.32
LMNA P02545 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
ALOX15 P16050 1/20 0.32
CYP2C19 P33261 1/20 0.32
CLK4 Q9HAZ1 1/20 0.32
AHR P35869 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26164391 0.95 HCRTR1 (0.33) MMP12MMP13PLA2G2APLA2G4AHCRTR1
SCHEMBL26164378 0.93 PLA2G2A (0.34) PLA2G2APLA2G4APLA2G10KDM4EATM
SCHEMBL26164375 0.90 KDM4E (0.39) KDM4EATMMAPK1HSD17B10USP2
SCHEMBL26164371 0.90 KDM4E (0.39) KDM4EATMMAPK1HSD17B10USP2
SCHEMBL26164402 0.89 MEN1 (0.34) MMP12MMP13PLA2G2APLA2G4AHCRTR1
SCHEMBL26164393 0.89 KDM4E (0.38) KDM4EATMMAPK1HSD17B10USP2
SCHEMBL26164386 0.89 KDM4E (0.34) PLA2G2APLA2G4APLA2G10KDM4EATM
SCHEMBL26164483 0.88 CHEK2 (0.34) PLA2G2APLA2G4APLA2G10KDM4EATM
SCHEMBL26164383 0.88 KDM4E (0.35) KDM4EATMMAPK1HSD17B10USP2
SCHEMBL26164563 0.87 PLA2G2A (0.36) PLA2G2APLA2G4APLA2G10KDM4EATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023096225-A1 HETEROCYCLIC COMPOUND, AND ORGANIC LIGHT-EMITTING DEVICE AND COMPOSITION FOR FORMING ORGANIC MATERIAL LAYER, COMPRISING SAME 엘티소재주식회사 2023-06-01 WO disclosed