SCHEMBL26164391

SCHEMBL26164391

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4ccc5c6c(cccc46)-c4ccc(-c6ccc7c(c6)oc6ccccc67)cc4O5)cc3)n2)cc1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCRTR1 O43613 1/20 0.33
PLA2G2A P14555 2/20 0.33
PLA2G4A P47712 2/20 0.33
MMP12 P39900 1/20 0.33
MMP13 P45452 1/20 0.33
PLA2G10 O15496 1/20 0.33
KDM4E B2RXH2 4/20 0.33
MAPK1 P28482 3/20 0.33
ATM Q13315 2/20 0.33
HSD17B10 Q99714 3/20 0.32
USP2 O75604 2/20 0.32
CYP1A2 P05177 2/20 0.32
CYP3A4 P08684 2/20 0.32
CYP2D6 P10635 2/20 0.32
ALOX15 P16050 2/20 0.32
CYP2C19 P33261 2/20 0.32
CLK4 Q9HAZ1 2/20 0.32
LMNA P02545 1/20 0.32
CYP2C9 P11712 1/20 0.32
AHR P35869 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26164381 0.95 MMP12 (0.34) HCRTR1PLA2G2APLA2G4AMMP12MMP13
SCHEMBL26164483 0.94 CHEK2 (0.34) PLA2G2APLA2G4APLA2G10KDM4EMAPK1
SCHEMBL26164484 0.90 MAPK1 (0.40) KDM4EMAPK1ATMHSD17B10USP2
SCHEMBL26164477 0.90 MAPK1 (0.40) KDM4EMAPK1ATMHSD17B10USP2
SCHEMBL26164388 0.89 KDM4E (0.39) KDM4EMAPK1ATMHSD17B10USP2
SCHEMBL26164497 0.89 KDM4E (0.39) KDM4EMAPK1ATMHSD17B10USP2
SCHEMBL26164481 0.89 MAPK1 (0.39) KDM4EMAPK1ATMHSD17B10USP2
SCHEMBL26164378 0.87 PLA2G2A (0.34) PLA2G2APLA2G4APLA2G10KDM4EMAPK1
SCHEMBL26164671 0.87 CHEK2 (0.34) PLA2G2APLA2G4APLA2G10KDM4EMAPK1
SCHEMBL26164478 0.87 MAPK1 (0.37) KDM4EMAPK1ATMHSD17B10USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023096225-A1 HETEROCYCLIC COMPOUND, AND ORGANIC LIGHT-EMITTING DEVICE AND COMPOSITION FOR FORMING ORGANIC MATERIAL LAYER, COMPRISING SAME 엘티소재주식회사 2023-06-01 WO disclosed