SCHEMBL26164402

SCHEMBL26164402

c1ccc(-c2ccc3c(c2)Oc2ccc(-c4nc(-c5ccc6c(c5)oc5ccccc56)c5ccccc5n4)c4cccc-3c24)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
ATM Q13315 1/20 0.34
MMP12 P39900 1/20 0.32
MMP13 P45452 1/20 0.32
USP2 O75604 3/20 0.31
CYP1A2 P05177 3/20 0.31
CYP3A4 P08684 3/20 0.31
CYP2D6 P10635 3/20 0.31
ALOX15 P16050 3/20 0.31
CYP2C19 P33261 3/20 0.31
HSD17B10 Q99714 3/20 0.31
CLK4 Q9HAZ1 3/20 0.31
LMNA P02545 2/20 0.31
TSHR P16473 2/20 0.31
MAPK1 P28482 2/20 0.31
CYP2C9 P11712 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TP53 P04637 1/20 0.31
ADORA2A P29274 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26164381 0.89 MMP12 (0.34) MEN1KMT2AATMMMP12MMP13
SCHEMBL26164399 0.89 MEN1 (0.43) MEN1KMT2AATMUSP2CYP1A2
SCHEMBL26164416 0.89 CYP1A2 (0.34) ATMMMP12MMP13CYP1A2LMNA
SCHEMBL26164329 0.88 MEN1 (0.33) MEN1KMT2AATMMMP12MMP13
SCHEMBL26164475 0.87 MEN1 (0.33) MEN1KMT2AATM
SCHEMBL26164403 0.87 ALDH1A1 (0.32) MEN1KMT2AATMCYP1A2CYP3A4
SCHEMBL26164400 0.86 ALDH1A1 (0.37) MEN1KMT2AATMUSP2CYP1A2
SCHEMBL26164330 0.86 MEN1 (0.33) MEN1KMT2AATMUSP2CYP1A2
SCHEMBL26164391 0.84 HCRTR1 (0.33) MEN1KMT2AATMMMP12MMP13
SCHEMBL26164421 0.84 MEN1 (0.43) MEN1KMT2AATMUSP2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023096225-A1 HETEROCYCLIC COMPOUND, AND ORGANIC LIGHT-EMITTING DEVICE AND COMPOSITION FOR FORMING ORGANIC MATERIAL LAYER, COMPRISING SAME 엘티소재주식회사 2023-06-01 WO disclosed