Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.83 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.83 |
| ▸ | RECQL | P46063 | 3/20 | 0.83 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.83 |
| ▸ | TSHR | P16473 | 3/20 | 0.83 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.83 |
| ▸ | MAPT | P10636 | 7/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | PGR | P06401 | 2/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.36 |
| ▸ | RXRA | P19793 | 6/20 | 0.34 |
| ▸ | RARA | P10276 | 4/20 | 0.34 |
| ▸ | RARB | P10826 | 4/20 | 0.34 |
| ▸ | RARG | P13631 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22506217 | 1.00 | ALDH1A1 (0.83) | ALDH1A1ALOX15RECQLHSD17B10TSHR | |
| SCHEMBL26670212 | 0.91 | ALDH1A1 (1.00) | ALDH1A1ALOX15RECQLHSD17B10TSHR | |
| SCHEMBL42367 | 0.91 | ALDH1A1 (1.00) | ALDH1A1ALOX15RECQLHSD17B10TSHR | |
| SCHEMBL340220 | 0.91 | ALDH1A1 (1.00) | ALDH1A1ALOX15RECQLHSD17B10TSHR | |
| SCHEMBL26670211 | 0.91 | ALDH1A1 (1.00) | ALDH1A1ALOX15RECQLHSD17B10TSHR | |
| SCHEMBL23576251 | 0.91 | ALDH1A1 (1.00) | ALDH1A1ALOX15RECQLHSD17B10TSHR | |
| SCHEMBL24736520 | 0.88 | ALDH1A1 (0.83) | ALDH1A1ALOX15RECQLHSD17B10TSHR | |
| SCHEMBL13419262 | 0.88 | ALDH1A1 (0.83) | ALDH1A1ALOX15RECQLHSD17B10TSHR | |
| SCHEMBL2616645 | 0.87 | ALDH1A1 (0.58) | ALDH1A1ALOX15RECQLHSD17B10TSHR | |
| SCHEMBL5074195 | 0.87 | ALDH1A1 (0.58) | ALDH1A1ALOX15RECQLHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9950067-B2 | Trans carotenoids, their synthesis, formulation and uses | Diffusion Pharmaceuticals, LLC (US) | 2018-04-24 | — | — | US | disclosed |
| US-20160199490-A1 | TRANS CAROTENOIDS, THEIR SYNTHESIS, FORMULATION AND USES | Diffusion Pharmaceuticals, LLC | 2016-07-14 | — | — | US | disclosed |
| US-20120095099-A1 | Trans carotenoids, their synthesis, formulation and uses | DIFFUSION PHARMACEUTICALS LLC (US) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160199490-A1 | TRANS CAROTENOIDS, THEIR SYNTHESIS, FORMULATION AND USES | TTPA, RBP4, TXNRD2 | ALDH1A1 3045/4885ALOX15 28/4885RECQL 2626/4885 |
| US-20120095099-A1 | Trans carotenoids, their synthesis, formulation and uses | TTPA, RBP4, TXNRD2 | ALDH1A1 3045/4885ALOX15 28/4885RECQL 2626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.