Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2616650 | 0.97 | ALDH1A1 (0.45) | ALDH1A1MAPTTDP1KDM4EPTGS1 | |
| SCHEMBL5071854 | 0.92 | PTGS1 (0.55) | ALDH1A1MAPTTDP1KDM4EPTGS1 | |
| SCHEMBL5071853 | 0.92 | PTGS1 (0.55) | ALDH1A1MAPTTDP1KDM4EPTGS1 | |
| SCHEMBL2616639 | 0.90 | ALDH1A1 (0.56) | ALDH1A1MAPTTDP1KDM4EPTGS1 | |
| SCHEMBL2630302 | 0.88 | HCAR2 (0.44) | ALDH1A1MAPTTDP1KDM4EPTGS1 | |
| SCHEMBL2616640 | 0.87 | HCAR2 (0.57) | ALDH1A1MAPTTDP1KDM4EPTGS1 | |
| SCHEMBL5873600 | 0.86 | PTGS1 (0.49) | ALDH1A1MAPTTDP1KDM4EPTGS1 | |
| SCHEMBL8503596 | 0.86 | PTGS1 (0.68) | ALDH1A1MAPTTDP1KDM4EPTGS1 | |
| SCHEMBL2616646 | 0.86 | PTGS1 (0.49) | ALDH1A1MAPTTDP1KDM4EPTGS1 | |
| SCHEMBL2616636 | 0.86 | PTGS1 (0.49) | ALDH1A1MAPTTDP1KDM4EPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9950067-B2 | Trans carotenoids, their synthesis, formulation and uses | Diffusion Pharmaceuticals, LLC (US) | 2018-04-24 | — | — | US | disclosed |
| US-9950067-B2 | Trans carotenoids, their synthesis, formulation and uses | Diffusion Pharmaceuticals, LLC (US) | 2018-04-24 | — | — | US | disclosed |
| US-20160199490-A1 | TRANS CAROTENOIDS, THEIR SYNTHESIS, FORMULATION AND USES | Diffusion Pharmaceuticals, LLC | 2016-07-14 | — | — | US | disclosed |
| US-20160199490-A1 | TRANS CAROTENOIDS, THEIR SYNTHESIS, FORMULATION AND USES | Diffusion Pharmaceuticals, LLC | 2016-07-14 | — | — | US | disclosed |
| US-20120095099-A1 | Trans carotenoids, their synthesis, formulation and uses | DIFFUSION PHARMACEUTICALS LLC (US) | 2012-04-19 | — | — | US | disclosed |
| US-20120095099-A1 | Trans carotenoids, their synthesis, formulation and uses | DIFFUSION PHARMACEUTICALS LLC (US) | 2012-04-19 | — | — | US | disclosed |
| US-8030350-B2 | Trans carotenoids, their synthesis, formulation and uses | DIFFUSION PHARMACEUTICALS LLC (US) | 2011-10-04 | — | — | US | disclosed |
| US-8030350-B2 | Trans carotenoids, their synthesis, formulation and uses | DIFFUSION PHARMACEUTICALS LLC (US) | 2011-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160199490-A1 | TRANS CAROTENOIDS, THEIR SYNTHESIS, FORMULATION AND USES | TTPA, RBP4, TXNRD2 | ALDH1A1 3045/4885MAPT 1885/4885TDP1 4025/4885 |
| US-20120095099-A1 | Trans carotenoids, their synthesis, formulation and uses | TTPA, RBP4, TXNRD2 | ALDH1A1 3045/4885MAPT 1885/4885TDP1 4025/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.