Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C3AR1 | Q16581 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | FURIN | P09958 | 1/20 | 0.33 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.33 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.33 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.33 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.32 |
| ▸ | NPY1R | P25929 | 3/20 | 0.32 |
| ▸ | NPY4R | P50391 | 3/20 | 0.32 |
| ▸ | NPY2R | P49146 | 1/20 | 0.32 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KLK7 | P49862 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALB | P02768 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | NMT2 | O60551 | 1/20 | 0.31 |
| ▸ | NMT1 | P30419 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25148126 | 0.88 | SIRT5 (0.38) | C3AR1CTDSP1NOD1SIRT5SIRT6 | |
| SCHEMBL20793387 | 0.82 | C3AR1 (0.41) | C3AR1CTDSP1QRFPRNOD1SIRT5 | |
| SCHEMBL20375713 | 0.82 | C3AR1 (0.41) | C3AR1CTDSP1QRFPRNOD1SIRT5 | |
| SCHEMBL18051173 | 0.82 | C3AR1 (0.41) | C3AR1CTDSP1QRFPRNOD1SIRT5 | |
| SCHEMBL22788849 | 0.81 | C3AR1 (0.36) | C3AR1CTDSP1QRFPRSIRT5SIRT6 | |
| SCHEMBL24860409 | 0.79 | C3AR1 (0.38) | C3AR1CTDSP1QRFPRNOD1SIRT5 | |
| SCHEMBL14887421 | 0.78 | DPP7 (0.41) | C3AR1NOD1SIRT5SIRT6SIRT1 | |
| SCHEMBL25448049 | 0.78 | DPP7 (0.41) | C3AR1NOD1SIRT5SIRT6SIRT1 | |
| SCHEMBL16645050 | 0.78 | DPP7 (0.41) | C3AR1NOD1SIRT5SIRT6SIRT1 | |
| SCHEMBL19203408 | 0.77 | SIRT5 (0.41) | C3AR1CTDSP1NOD1SIRT5SIRT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023102507-A1 | MACROCYCLIC IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-06-08 | — | — | WO | disclosed |