Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.38 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.36 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | KISS1R | Q969F8 | 3/20 | 0.34 |
| ▸ | NPY4R | P50391 | 6/20 | 0.33 |
| ▸ | NPY1R | P25929 | 4/20 | 0.33 |
| ▸ | NPY2R | P49146 | 3/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.33 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.33 |
| ▸ | ECE1 | P42892 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
| ▸ | ALB | P02768 | 1/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | NMT2 | O60551 | 1/20 | 0.32 |
| ▸ | NMT1 | P30419 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11913625 | 0.88 | C3AR1 (0.47) | SIRT5C3AR1NOD1ECE1CTDSP1 | |
| SCHEMBL12222096 | 0.88 | C3AR1 (0.47) | SIRT5C3AR1NOD1ECE1CTDSP1 | |
| SCHEMBL25875020 | 0.88 | C3AR1 (0.47) | SIRT5C3AR1NOD1ECE1CTDSP1 | |
| SCHEMBL26167079 | 0.88 | C3AR1 (0.38) | SIRT5C3AR1SIRT6SIRT1NPY4R | |
| SCHEMBL16645050 | 0.87 | DPP7 (0.41) | SIRT5C3AR1SIRT6SIRT1KISS1R | |
| SCHEMBL25448049 | 0.87 | DPP7 (0.41) | SIRT5C3AR1SIRT6SIRT1KISS1R | |
| SCHEMBL14887421 | 0.87 | DPP7 (0.41) | SIRT5C3AR1SIRT6SIRT1KISS1R | |
| SCHEMBL23760646 | 0.86 | SIRT5 (0.36) | SIRT5C3AR1SIRT6SIRT1KISS1R | |
| SCHEMBL18511502 | 0.85 | FOLH1 (0.42) | SIRT5C3AR1SIRT1NPY4RNPY1R | |
| SCHEMBL25092038 | 0.84 | SIRT5 (0.44) | SIRT5C3AR1SIRT6SIRT1KISS1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11701427-B2 | Diels-alder conjugation methods | REGENERON PHARMACEUTICALS, INC. (US) | 2023-07-18 | — | — | US | disclosed |
| WO-2023061405-A1 | HIGHLY-STABLE TARGETED LINKER-DRUG CONJUGATE | 成都科岭源医药技术有限公司 | 2023-04-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11701427-B2 | Diels-alder conjugation methods | GLUL, TGM2, GLS | SIRT5 1416/4885C3AR1 2197/4885SIRT6 1056/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.