Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 4/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19658338 | 1.00 | EPHX1 (0.46) | EPHX1CES2CES1KDM4EHTT | |
| SCHEMBL22872257 | 1.00 | EPHX1 (0.46) | EPHX1CES2CES1KDM4EHTT | |
| SCHEMBL18735714 | 1.00 | EPHX1 (0.46) | EPHX1CES2CES1KDM4EHTT | |
| SCHEMBL25574876 | 0.93 | EPHX1 (0.40) | EPHX1CES2CES1KDM4EHTT | |
| SCHEMBL13872421 | 0.93 | EPHX1 (0.40) | EPHX1CES2CES1KDM4EHTT | |
| SCHEMBL28004056 | 0.91 | EPHX1 (0.41) | EPHX1CES2CES1KDM4EHTT | |
| SCHEMBL18532477 | 0.90 | EPHX1 (0.39) | EPHX1KDM4EHTTSMN1; SMN2PSEN1 | |
| SCHEMBL1115372 | 0.89 | KDM4E (0.47) | KDM4EHTTSMN1; SMN2 | |
| SCHEMBL18435274 | 0.89 | KDM4E (0.47) | KDM4EHTTSMN1; SMN2 | |
| SCHEMBL16141882 | 0.89 | KDM4E (0.47) | KDM4EHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 172 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11874434-B2 | Ophthalmic devices comprising photochromic materials with reactive substituents | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2024-01-16 | — | — | US | disclosed |
| US-11874434-B2 | Ophthalmic devices comprising photochromic materials with reactive substituents | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2024-01-16 | — | — | US | disclosed |
| WO-2022115719-A1 | PD-L1 BINDING PEPTIDES AND PEPTIDE COMPLEXES AND METHODS OF USE THEREOF | FRED HUTCHINSON CANCER RESEARCH CENTER (US) | 2022-06-02 | — | — | WO | disclosed |
| US-20220137262-A1 | OPHTHALMIC DEVICES COMPRISING PHOTOCHROMIC MATERIALS WITH REACTIVE SUBSTITUENTS | JOHNSON & JOHNSON VISION CARE (US) | 2022-05-05 | — | — | US | disclosed |
| US-11256002-B2 | Ophthalmic devices comprising photochromic materials with reactive substituents | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2022-02-22 | — | — | US | disclosed |
| US-20210171811-A1 | ADHESIVE METHOD USING TWO-COMPONENT ADHESIVES BASED ON COMPOUNDS HAVING CYCLOTHIOCARBONATE UNITS | BASF SE (DE) | 2021-06-10 | — | — | US | disclosed |
| EP-3283550-B1 | CATALYST CONTAINING AMIDINE GROUPS | SIKA TECH AG (CH) | 2020-12-16 | — | — | EP | disclosed |
| US-20200385518-A1 | FLUORINATED ETHER POLYMER, THE PREPARATION METHOD THERFORE AND USE THEREOF | AKZO NOBEL COATINGS INTERNATIONAL B.V. (NL) | 2020-12-10 | — | — | US | disclosed |
| EP-3294803-B1 | GUANIDINE GROUP CONTAINING CATALYST | SIKA TECH AG (CH) | 2020-12-09 | — | — | EP | disclosed |
| US-10689317-B2 | Methods of making fused ring compounds | TRANSITIONS OPTICAL, INC. (US) | 2020-06-23 | — | — | US | disclosed |
| US-20080160452-A1 | Developer for light sensitive planographic printing plate material and manufacturing process of planographic printing plate employing the same | KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) | 2008-07-03 | — | — | US | disclosed |
| US-20080102406-A1 | LIGHT SENSITIVE PLANOGRAPHIC PRINTING PLATE MATERIAL AND MANUFACTURING PROCESS OF PRINTING PLATE EMPLOYING THE SAME | KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) | 2008-05-01 | — | — | US | disclosed |
| US-20080103301-A1 | PHOTOCHROMIC MATERIALS DEMONSTRATING IMPROVED FADE RATES | TRANSITIONS OPTICAL, INC. (US) | 2008-05-01 | — | — | US | disclosed |
| US-20080103301-A1 | PHOTOCHROMIC MATERIALS DEMONSTRATING IMPROVED FADE RATES | TRANSITIONS OPTICAL, INC. (US) | 2008-05-01 | — | — | US | disclosed |
| WO-2007140071-A1 | PHOTOCHROMIC MATERIALS COMPRISING HALOALKYL GROUPS | TRANSITIONS OPTICAL, INC. (US) | 2007-12-06 | — | — | WO | disclosed |
| US-20070278460-A1 | Photochromic materials comprising metallocenyl groups | TRANSITIONS OPTICAL LIMITED (IE) | 2007-12-06 | — | — | US | disclosed |
| US-20070278460-A1 | Photochromic materials comprising metallocenyl groups | TRANSITIONS OPTICAL LIMITED (IE) | 2007-12-06 | — | — | US | disclosed |
| US-20070278461-A1 | PHOTOCHROMIC MATERIALS COMPRISING HALOALKYL GROUPS | TRANSITIONS OPTICAL, INC. (US) | 2007-12-06 | — | — | US | disclosed |
| US-20070278461-A1 | PHOTOCHROMIC MATERIALS COMPRISING HALOALKYL GROUPS | TRANSITIONS OPTICAL, INC. (US) | 2007-12-06 | — | — | US | disclosed |
| US-7226971-B2 | Polyester resin with carbamate functionality, a method of preparing the resin, and a coating composition utilizing the resin | BASF CORPORATION (US) | 2007-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080103301-A1 | PHOTOCHROMIC MATERIALS DEMONSTRATING IMPROVED FADE RATES | PNPO, FLAD1, CRY2 | EPHX1 728/4885CES2 946/4885CES1 1905/4885 |
| US-10689317-B2 | Methods of making fused ring compounds | CYP2B6, CYP2A6, INTS6 | EPHX1 480/4885CES2 650/4885CES1 450/4885 |
| US-20210171811-A1 | ADHESIVE METHOD USING TWO-COMPONENT ADHESIVES BASED ON COMPOUNDS HAVING CYCLOTHIOCARBONATE UNITS | CDH1, EPCAM, ICAM1 | EPHX1 1541/4885CES2 629/4885CES1 4055/4885 |
| US-20070278461-A1 | PHOTOCHROMIC MATERIALS COMPRISING HALOALKYL GROUPS | TELO2, EYA3, CRY2 | EPHX1 1636/4885CES2 667/4885CES1 2165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.