Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SPR | P35270 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.34 |
| ▸ | MLYCD | O95822 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26730051 | 0.83 | HCAR3 (0.46) | KMT2APDK2SMN1; SMN2THRATHRB | |
| SCHEMBL2228382 | 0.78 | KMT2A (0.63) | KMT2AHSP90AA1TP53SMN1; SMN2HPGD | |
| SCHEMBL471656 | 0.78 | HPGD (0.50) | KMT2AHSP90AA1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL16915230 | 0.76 | MCHR1 (0.47) | KMT2ASMN1; SMN2THRATHRBHPGD | |
| SCHEMBL20858882 | 0.74 | TSHR (0.45) | KMT2AHSP90AA1PDK2SMN1; SMN2THRA | |
| SCHEMBL16994787 | 0.72 | SMN1; SMN2 (0.51) | KMT2AHSP90AA1PDK2HTTSMN1; SMN2 | |
| SCHEMBL10282503 | 0.72 | SMN1; SMN2 (0.48) | KMT2AHSP90AA1HTTSMN1; SMN2HPGD | |
| SCHEMBL4518825 | 0.72 | KMT2A (0.41) | KMT2AHSP90AA1PDK2HTTSMN1; SMN2 | |
| SCHEMBL12213211 | 0.71 | SMN1; SMN2 (0.50) | KMT2AHSP90AA1HTTSMN1; SMN2HPGD | |
| SCHEMBL26730049 | 0.71 | HSP90AA1 (0.36) | KMT2AHSP90AA1SPRPDK2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192686-A1 | 1H-PYRROLO[2,3-B]PYRIDINES AND PREPARATION AND USES THEREOF | TENARX, INC. | 2023-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192686-A1 | 1H-PYRROLO[2,3-B]PYRIDINES AND PREPARATION AND USES THEREOF | DYRK1A, DYRK1B, DYRK2 | KMT2A 1738/4885HSP90AA1 1718/4885TP53 46/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.