SCHEMBL26187054

SCHEMBL26187054

CC(C)(C)OC(=O)N1CC[C@H](C(F)(F)c2ccc(Br)cc2)C1

nearest known ligand 0.45

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ USP30 Q70CQ3 2/20 0.45
▸ FPR2 P25090 6/20 0.45
▸ FPR3 P25089 2/20 0.45
▸ RORC P51449 4/20 0.45
▸ GPR119 Q8TDV5 3/20 0.43
▸ PDE4B Q07343 1/20 0.42
▸ PTPN2 P17706 1/20 0.42
▸ PTPN1 P18031 1/20 0.42
▸ PTPN6 P29350 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26187095 1.00 USP30 (0.45) USP30FPR2FPR3RORCGPR119
SCHEMBL24762233 0.93 FPR2 (0.47) FPR2FPR3RORCGPR119PTPN2
SCHEMBL17541957 0.90 RORC (0.49) USP30FPR2FPR3RORC
SCHEMBL23211982 0.82 MAPT (0.56) GPR119PTPN2PTPN1PTPN6
SCHEMBL21752606 0.80 GPR119 (0.59) RORCGPR119PTPN2PTPN1PTPN6
SCHEMBL15675294 0.80 FPR2 (0.49) USP30FPR2FPR3RORCPDE4B
SCHEMBL15675293 0.80 FPR2 (0.49) USP30FPR2FPR3RORCPDE4B
SCHEMBL14375625 0.80 FPR2 (0.49) USP30FPR2FPR3RORCPDE4B
SCHEMBL17729471 0.79 MAPT (0.52) USP30RORCGPR119
SCHEMBL18321686 0.79 FPR2 (0.47) FPR2FPR3GPR119PTPN2PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4508031-A1 NOVEL SUBSTITUTED FLUORINATED N-PROPYL-PYRROLIDINE COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF Sanofi (FR) 2025-02-19 — — EP disclosed
WO-2023198879-A1 NOVEL SUBSTITUTED FLUORINATED N-PROPYL-PYRROLIDINE COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF SANOFI (FR) 2023-10-19 — — WO disclosed
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