SCHEMBL26190812

SCHEMBL26190812

CS(=O)(=O)C(F)(F)C(OC(=O)C12CC3CC(C1)C(=O)C(C3)C2)C(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYP17A1 P05093 5/20 0.35
CYP19A1 P11511 5/20 0.35
EPHX2 P34913 1/20 0.33
PRKCA P17252 1/20 0.33
TSHR P16473 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18133301 0.90 EPHX2 (0.35) CYP17A1CYP19A1EPHX2PRKCATSHR
SCHEMBL23559488 0.90 EPHX2 (0.35) CYP17A1CYP19A1EPHX2PRKCATSHR
SCHEMBL6448541 0.90 EPHX2 (0.35) CYP17A1CYP19A1EPHX2PRKCATSHR
SCHEMBL26190788 0.89 PRKCA (0.40) CYP17A1CYP19A1PRKCATSHRNPSR1
SCHEMBL26190682 0.88 CYP17A1 (0.34) CYP17A1CYP19A1EPHX2PRKCATSHR
SCHEMBL19042387 0.88 EPHX2 (0.33) CYP17A1CYP19A1EPHX2PRKCATSHR
SCHEMBL22797667 0.87 EPHX2 (0.33) CYP17A1CYP19A1EPHX2PRKCATSHR
SCHEMBL13642226 0.85 CYP17A1 (0.38) CYP17A1CYP19A1EPHX2PRKCATSHR
SCHEMBL2130379 0.85 CYP17A1 (0.32) CYP17A1CYP19A1PRKCATSHRNPSR1
SCHEMBL14554295 0.81 EPHX2 (0.35) CYP17A1CYP19A1EPHX2PRKCATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230341772-A1 RADIATION-SENSITIVE RESIN COMPOSITION AND METHOD FOR FORMING RESIST PATTERN JSR CORPORATION (JP) 2023-10-26 US disclosed
US-11747725-B2 Radiation-sensitive resin composition and method for forming resist pattern JSR CORPORATION (JP) 2023-09-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230341772-A1 RADIATION-SENSITIVE RESIN COMPOSITION AND METHOD FOR FORMING RESIST PATTERN RER1, XRCC5, F12 CYP17A1 2352/4885CYP19A1 2673/4885EPHX2 655/4885
US-11747725-B2 Radiation-sensitive resin composition and method for forming resist pattern RER1, AFF1, RAD51 CYP17A1 2648/4885CYP19A1 1731/4885EPHX2 430/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.