Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 3/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | ATR | Q13535 | 1/20 | 0.34 |
| ▸ | STK17B | O94768 | 1/20 | 0.34 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.33 |
| ▸ | CCR9 | P51686 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31543097 | 0.78 | HSP90AA1 (0.39) | JAK1CDK9CCR9LMNA | |
| SCHEMBL31543369 | 0.78 | HSP90AA1 (0.39) | JAK1CDK9CCR9LMNA | |
| SCHEMBL28575805 | 0.78 | STK17B (0.43) | JAK1TRPA1ATRSTK17BSTK17A | |
| SCHEMBL30482406 | 0.77 | MTNR1A (0.46) | CDK9STK17BSTK17ASCN9A | |
| SCHEMBL25378725 | 0.77 | MTNR1A (0.46) | CDK9STK17BSTK17ASCN9A | |
| SCHEMBL4756322 | 0.71 | NPC1 (0.44) | JAK1LMNAKMT2ACYP1A2CYP3A4 | |
| SCHEMBL16879925 | 0.69 | METAP1 (0.40) | KMT2ASCN9ACYP3A4 | |
| SCHEMBL16332510 | 0.69 | KDM4E (0.46) | JAK1STK17BSTK17AMAPKAPK2LMNA | |
| SCHEMBL12931891 | 0.69 | ATR (0.47) | TRPA1ATRSTK17BSTK17ACA12 | |
| SCHEMBL2768194 | 0.68 | GSK3B (0.47) | CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146786-A1 | IMIDAZOPYRIDINE INHIBITORS OF TYROSINE KINASE | BRIDGENE BIOSCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |