Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CCR9 | P51686 | 1/20 | 0.34 |
| ▸ | PRPS1 | P60891 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31543369 | 1.00 | HSP90AA1 (0.39) | HSP90AA1HSP90AB1GABRG2GABRB3GABRA5 | |
| SCHEMBL5840794 | 0.80 | ALDH1A1 (0.43) | HSP90AA1HSP90AB1POLBKDM4EALDH1A1 | |
| SCHEMBL5840858 | 0.80 | ALDH1A1 (0.43) | HSP90AA1HSP90AB1POLBKDM4EALDH1A1 | |
| SCHEMBL31543222 | 0.79 | GABRG2 (0.41) | HSP90AA1HSP90AB1GABRG2GABRB3GABRA5 | |
| SCHEMBL31543605 | 0.79 | GABRG2 (0.41) | HSP90AA1HSP90AB1GABRG2GABRB3GABRA5 | |
| SCHEMBL26192157 | 0.78 | JAK1 (0.36) | CCR9JAK1LMNACDK9 | |
| SCHEMBL16441377 | 0.77 | HSP90AA1 (0.46) | HSP90AA1HSP90AB1GABRG2GABRB3GABRA5 | |
| SCHEMBL4816124 | 0.76 | GABRG2 (0.47) | HSP90AA1HSP90AB1GABRG2GABRB3GABRA5 | |
| SCHEMBL832385 | 0.76 | BRD4 (0.40) | GABRG2GABRB3GABRA5GABRA1GABRA2 | |
| SCHEMBL7479053 | 0.76 | HTR6 (0.44) | HSP90AA1HSP90AB1GABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119654322-A | TYK2 inhibitors | 渤健马萨诸塞州股份有限公司 | 2025-03-18 | — | — | CN | disclosed |