Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.37 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 7/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL751146 | 1.00 | TP53 (0.38) | TP53ALDH1A1HPGDNOD2NOD1 | |
| SCHEMBL4572449 | 0.93 | NOD1 (0.36) | TP53ALDH1A1HPGDNOD2NOD1 | |
| SCHEMBL733302 | 0.93 | ALDH1A1 (0.39) | TP53ALDH1A1HPGDNOD2NOD1 | |
| SCHEMBL732561 | 0.92 | ALDH1A1 (0.39) | TP53ALDH1A1HPGDNOD2NOD1 | |
| SCHEMBL734365 | 0.92 | ALDH1A1 (0.39) | TP53ALDH1A1HPGDNOD2NOD1 | |
| SCHEMBL734277 | 0.92 | ALDH1A1 (0.40) | TP53ALDH1A1HPGDNOD2NOD1 | |
| SCHEMBL732677 | 0.91 | NOD1 (0.35) | NOD2NOD1DHODHPDE4APDE4B | |
| SCHEMBL733189 | 0.90 | ALDH1A1 (0.40) | TP53ALDH1A1HPGDNOD2NOD1 | |
| SCHEMBL734022 | 0.90 | ALDH1A1 (0.39) | TP53ALDH1A1HPGDNOD2NOD1 | |
| SCHEMBL731980 | 0.90 | TRPM2 (0.39) | TP53ALDH1A1HPGDNOD2NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120101131-A1 | Aminotetrahydroindazoloacetic Acids | CHEN LI (CN) | 2012-04-26 | — | — | US | disclosed |
| US-20120101131-A1 | Aminotetrahydroindazoloacetic Acids | CHEN LI (CN) | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101131-A1 | Aminotetrahydroindazoloacetic Acids | HRH2, HRH1, HRH4 | TP53 4252/4885ALDH1A1 507/4885HPGD 126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.