⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14778173 | 0.88 | CA1 (0.36) | — | |
| SCHEMBL27187 | 0.88 | — | — | |
| SCHEMBL14523162 | 0.86 | CA1 (0.34) | — | |
| SCHEMBL25949 | 0.82 | — | — | |
| SCHEMBL17493638 | 0.81 | — | — | |
| SCHEMBL4792651 | 0.80 | ALDH1A1 (0.58) | — | |
| SCHEMBL6907900 | 0.79 | — | — | |
| SCHEMBL2102930 | 0.78 | ALDH1A1 (0.62) | — | |
| SCHEMBL1668988 | 0.78 | ALDH1A1 (0.62) | — | |
| SCHEMBL4867685 | 0.78 | ALDH1A1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 404 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9388105-B2 | Production of hydroxy ether hydrocarbons by liquid phase hydrogenolysis of cyclic acetals or cyclic ketals | EASTMAN CHEMICAL COMPANY (US) | 2016-07-12 | — | — | US | claimed |
| US-9382179-B2 | Nickel modified catalyst for the production of hydroxy ether hydrocarbons by vapor phase hydrogenolysis of cyclic acetals and ketals | EASTMAN CHEMICAL COMPANY (US) | 2016-07-05 | — | — | US | claimed |
| US-9000229-B2 | Production of hydroxy ether hydrocarbons by vapor phase hydrogenolysis of cyclic acetals and ketals | EASTMAN CHEMICAL COMPANY (US) | 2015-04-07 | — | — | US | claimed |
| US-8969598-B2 | Production of cyclic acetals or ketals using liquid-phase acid catalysts | EASTMAN CHEMICAL COMPANY (US) | 2015-03-03 | — | — | US | claimed |
| US-20140303404-A1 | NICKEL MODIFIED CATALYST FOR THE PRODUCTION OF HYDROXY ETHER HYDROCARBONS BY VAPOR PHASE HYDROGENOLYSIS OF CYCLIC ACETALS AND KETALS | EASTMAN CHEMICAL COMPANY (US) | 2014-10-09 | — | — | US | claimed |
| US-8829206-B2 | Production of cyclic acetals or ketals using solid acid catalysts | EASTMAN CHEMICAL COMPANY (US) | 2014-09-09 | — | — | US | claimed |
| US-8829207-B2 | Production of cyclic acetals by reactive distillation | EASTMAN CHEMICAL COMPANY (US) | 2014-09-09 | — | — | US | claimed |
| US-8785697-B2 | Nickel modified catalyst for the production of hydroxy ether hydrocarbons by vapor phase hydrogenolysis of cyclic acetals and ketals | EASTMAN CHEMICAL COMPANY (US) | 2014-07-22 | — | — | US | claimed |
| US-20130102641-A1 | PRODRUGS OF GABA ANALOGS, COMPOSITIONS AND USES THEREOF | XENOPORT, INC. (US) | 2013-04-25 | — | — | US | claimed |
| US-20120330069-A1 | PRODUCTION OF HYDROXY ETHER HYDROCARBONS BY LIQUID PHASE HYDROGENOLYSIS OF CYCLIC ACETALS OR CYCLIC KETALS | EASTMAN CHEMICAL COMPANY (US) | 2012-12-27 | — | — | US | claimed |
| EP-1902714-A1 | Prodrugs of gaba analogs, compositions and uses thereof | Xenoport, Inc. (US) | 2008-03-26 | — | — | EP | claimed |
| EP-1404324-B1 | PRODRUGS OF GABA ANALOGS, COMPOSITIONS AND USES THEREOF | XENOPORT INC (US) | 2007-12-05 | — | — | EP | claimed |
| US-7060727-B2 | Prodrugs of fused GABA analogs, pharmaceutical compositions and uses thereof | XENOPORT, INC. (US) | 2006-06-13 | — | — | US | claimed |
| US-20040147455-A1 | Prodrugs of fused GABA analogs, pharmaceutical compositions and uses thereof | XENOPORT, INC. | 2004-07-29 | — | — | US | claimed |
| WO-2004052360-A1 | PRODRUGS OF FUSED GABA ANALOGS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | XENOPORT, INC. (US) | 2004-06-24 | — | — | WO | claimed |
| US-20030176398-A1 | Prodrugs of GABA analogs, compositions and uses thereof | HPS INVESTMENT PARTNERS, LLC, AS ADMINISTRATIVE AGENT | 2003-09-18 | — | — | US | claimed |
| EP-1104401-B1 | PEROXIDES, THEIR PREPARATION PROCESS AND USE | AKZO NOBEL NV (NL) | 2002-12-04 | — | — | EP | claimed |
| US-6384287-B1 | REACTING A KETONE PEROXIDE WITH AN ALKYL VINYL ETHER OR AN ACETAL IN THE PRESENCE OF A CATALYST TO YIELD COMPOUNDS AS POLYMERIZATION INITIATORS, CURING AGENTS FOR UNSATURATED POLYESTERS, AND MODIFYING AGENTS | AKZO NOBEL NV (NL) | 2002-05-07 | — | — | US | claimed |
| EP-1104401-A1 | PEROXIDES, THEIR PREPARATION PROCESS AND USE | Akzo Nobel N.V. (NL) | 2001-06-06 | — | — | EP | claimed |
| WO-2000009478-A1 | PEROXIDES, THEIR PREPARATION PROCESS AND USE | AKZO NOBEL N.V. (NL) | 2000-02-24 | — | — | WO | claimed |