Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.41 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19872925 | 0.97 | GLA (0.41) | GLATDP1HDAC3HDAC4HDAC1 | |
| SCHEMBL35300 | 0.83 | GLA (0.50) | GLATDP1HDAC3HDAC4HDAC1 | |
| SCHEMBL19058802 | 0.82 | MAPT (0.47) | GLATDP1HDAC3HDAC4HDAC1 | |
| SCHEMBL5069733 | 0.79 | LMNA (0.38) | GLATDP1HDAC3HDAC4HDAC1 | |
| SCHEMBL18774307 | 0.79 | MAPT (0.44) | GLATDP1HDAC3HDAC4HDAC1 | |
| SCHEMBL19872767 | 0.79 | MAPT (0.44) | GLATDP1HDAC3HDAC4HDAC1 | |
| SCHEMBL22080876 | 0.78 | ALOX5 (0.40) | MAOBEGFRMAOA | |
| SCHEMBL27391990 | 0.76 | MAPT (0.48) | GLATDP1HDAC3HDAC4HDAC1 | |
| SCHEMBL24209246 | 0.76 | GLA (0.43) | GLATDP1HDAC3HDAC4HDAC1 | |
| SCHEMBL19221395 | 0.76 | GLA (0.40) | GLATDP1HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230280275-A1 | PHOTOACTIVATABLE VIBRATIONAL PROBES AND USES THEREOF | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2023-09-07 | — | — | US | disclosed |