SCHEMBL5069733

SCHEMBL5069733

C=CC(C=Cc1ccccc1)=CC=CC#N

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 6/20 0.38
MAPT P10636 4/20 0.38
ALDH1A1 P00352 3/20 0.38
HDAC3 O15379 2/20 0.38
HDAC4 P56524 2/20 0.38
HDAC1 Q13547 2/20 0.38
HDAC2 Q92769 2/20 0.38
HDAC8 Q9BY41 2/20 0.38
HDAC6 Q9UBN7 2/20 0.38
PLIN1 O60240 2/20 0.38
RECQL P46063 2/20 0.38
PLIN5 Q00G26 2/20 0.38
ABHD5 Q8WTS1 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
MCL1 Q07820 2/20 0.38
TNKS O95271 1/20 0.38
HCAR2 Q8TDS4 1/20 0.38
HDAC7 Q8WUI4 1/20 0.38
HDAC10 Q969S8 1/20 0.38
HDAC11 Q96DB2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL116598 0.79 LMNA (0.39) LMNAMAPTALDH1A1HDAC3HDAC4
SCHEMBL26201152 0.79 GLA (0.43) LMNAMAPTALDH1A1HDAC3HDAC4
SCHEMBL1019465 0.78 MCL1 (0.32) LMNAMAPTALDH1A1HDAC3HDAC4
SCHEMBL19058802 0.78 MAPT (0.47) LMNAMAPTALDH1A1HDAC3HDAC4
SCHEMBL19591781 0.78 GLA (0.46) LMNAMAPTALDH1A1HDAC3HDAC4
SCHEMBL19872925 0.76 GLA (0.41) LMNAMAPTALDH1A1HDAC3HDAC4
SCHEMBL11206156 0.76 LMNA (0.33) LMNAMAPTALDH1A1HDAC3HDAC4
SCHEMBL123960 0.75 LMNA (0.46) LMNAMAPTALDH1A1HDAC3HDAC4
SCHEMBL19872767 0.75 MAPT (0.44) LMNAMAPTALDH1A1HDAC3HDAC4
SCHEMBL18774307 0.75 MAPT (0.44) LMNAMAPTALDH1A1HDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1796904-A1 POLYMER ASSEMBLIES WITH DECORATIVE SURFACES E.I.Du pont de nemours and company (US) 2007-06-20 EP claimed
WO-2006041771-A1 POLYMER ASSEMBLIES WITH DECORATIVE SURFACES E.I. DUPONT DE NEMOURS AND COMPANY (US) 2006-04-20 WO claimed
EP-1890867-A1 DECORATIVE POLYMERIC MULTILAYER STRUCTURES E.I. DUPONT DE NEMOURS AND COMPANY (US) 2008-02-27 EP disclosed
WO-2006138310-A1 DECORATIVE POLYMERIC MULTILAYER STRUCTURES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2006-12-28 WO disclosed
EP-0746576-A1 PROCESS FOR THE PREPARATION OF MULTIMODAL ABS POLYMERS THE DOW CHEMICAL COMPANY (US) 1996-12-11 EP disclosed
WO-1995022570-A1 PROCESS FOR THE PREPARATION OF MULTIMODAL ABS POLYMERS THE DOW CHEMICAL COMPANY (US) 1995-08-24 WO disclosed