Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | PDIA6 | Q15084 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26200999 | 0.85 | THRA (0.43) | ELANEPDIA6THRATHRBALDH1A1 | |
| SCHEMBL26201092 | 0.83 | ELANE (0.49) | ELANEMCL1THRATHRBALDH1A1 | |
| SCHEMBL26200980 | 0.79 | MAPT (0.51) | THRATHRBALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL26201485 | 0.78 | FFAR1 (0.40) | ELANELMNATHRAALDH1A1KDM4E | |
| SCHEMBL26200983 | 0.77 | LMNA (0.38) | ELANEMCL1LMNAPDIA6ALDH1A1 | |
| SCHEMBL30388036 | 0.77 | LMNA (0.36) | ELANEMCL1LMNAPDIA6THRA | |
| Bromide SCHEMBL25432984 | 0.75 | CHRNA7 (0.45) | — | |
| Bromide SCHEMBL30388039 | 0.75 | CHRNA7 (0.45) | — | |
| SCHEMBL26200979 | 0.75 | DRD2 (0.34) | LMNAALDH1A1MAPTHPGDL3MBTL1 | |
| SCHEMBL26200975 | 0.74 | GRIN2D (0.39) | SMN1; SMN2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230280275-A1 | PHOTOACTIVATABLE VIBRATIONAL PROBES AND USES THEREOF | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2023-09-07 | — | — | US | disclosed |