SCHEMBL26201436

SCHEMBL26201436

CO[C@@H]1[C@H](OP(=O)(O)OC[C@H]2O[C@@H](n3cnc4c(=O)[nH]c(N)nc43)[C@H](O)[C@@H]2O)C(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O[C@H]1n1cnc2c(=O)[nH]c(N)nc21

nearest known ligand 0.68

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 1/20 0.68
FUT5 Q11128 1/20 0.68
RNASEL Q05823 6/20 0.67
KRAS P01116 2/20 0.65
NT5E P21589 1/20 0.64
P2RY6 Q15077 2/20 0.61
P2RY2 P41231 1/20 0.61
P2RY4 P51582 1/20 0.61
P2RX3 P56373 2/20 0.59
ENPP1 P22413 2/20 0.59
P2RY1 P47900 2/20 0.59
P2RX1 P51575 1/20 0.59
P2RY11 Q96G91 1/20 0.59
P2RX4 Q99571 1/20 0.59
IMPDH2 P12268 1/20 0.59
IMPDH1 P20839 1/20 0.59
DCPS Q96C86 1/20 0.58
P2RY12 Q9H244 1/20 0.58
HINT1 P49773 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26204432 1.00 TGM2 (0.68) TGM2FUT5RNASELKRASNT5E
SCHEMBL22678637 0.96 TGM2 (0.69) TGM2FUT5RNASELKRASNT5E
SCHEMBL26201639 0.95 RNASEL (0.73) TGM2FUT5RNASELP2RY2P2RX3
SCHEMBL26201887 0.95 RNASEL (0.73) TGM2FUT5RNASELP2RY2P2RX3
SCHEMBL26577103 0.95 RNASEL (0.73) TGM2FUT5RNASELP2RY2P2RX3
SCHEMBL26578079 0.95 RNASEL (0.73) TGM2FUT5RNASELP2RY2P2RX3
SCHEMBL24941695 0.94 RNASEL (0.72) TGM2RNASELP2RY2P2RX3P2RY1
SCHEMBL26067694 0.94 RNASEL (0.72) TGM2RNASELP2RY2P2RX3P2RY1
SCHEMBL26209310 0.94 RNASEL (0.72) TGM2RNASELP2RY2P2RX3P2RY1
SCHEMBL26216247 0.92 RNASEL (0.62) TGM2FUT5RNASELKRASNT5E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4261217-A1 COMPOUND FOR RNA CAPPING AND APPLICATION OF COMPOUND Guangzhou Henovcom Bioscience Co., Ltd. (CN) 2023-10-18 EP disclosed
WO-2023159930-A1 COMPOUND FOR RNA CAPPING AND APPLICATION OF COMPOUND 广州市恒诺康医药科技有限公司 2023-08-31 WO disclosed