Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 10/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.49 |
| ▸ | TSHR | P16473 | 5/20 | 0.49 |
| ▸ | EIF2AK4 | Q9P2K8 | 2/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.45 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30556652 | 0.89 | CYP2D6 (0.52) | CYP2D6ALDH1A1HSD17B10CYP1A2CYP3A4 | |
| SCHEMBL26051212 | 0.84 | ALDH1A1 (0.56) | CYP2D6ALDH1A1HSD17B10CYP1A2CYP3A4 | |
| SCHEMBL26046515 | 0.83 | ALDH1A1 (0.58) | CYP2D6ALDH1A1HSD17B10CYP1A2CYP3A4 | |
| SCHEMBL26046514 | 0.83 | ALDH1A1 (0.58) | CYP2D6ALDH1A1HSD17B10CYP1A2CYP3A4 | |
| SCHEMBL30556699 | 0.81 | HSD17B10 (0.44) | CYP2D6ALDH1A1HSD17B10CYP1A2CYP3A4 | |
| SCHEMBL30556651 | 0.80 | SORD (0.45) | CYP2D6ALDH1A1HSD17B10CYP1A2CYP3A4 | |
| SCHEMBL30637363 | 0.79 | SORD (0.45) | CYP2D6ALDH1A1HSD17B10CYP1A2TSHR | |
| SCHEMBL30556663 | 0.78 | ALDH1A1 (0.46) | CYP2D6ALDH1A1HSD17B10CYP1A2CYP3A4 | |
| SCHEMBL26047171 | 0.76 | SORD (0.40) | CYP2D6ALDH1A1HSD17B10CYP1A2TSHR | |
| SCHEMBL7904079 | 0.76 | SORD (0.55) | ALDH1A1HSD17B10TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023163712-A1 | MODULATORS OF MYC FAMILY PROTO-ONCOGENE PROTEIN | NALO THERAPEUTICS (US) | 2023-08-31 | — | — | WO | disclosed |