Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORD | Q00796 | 1/20 | 0.45 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | OGA | O60502 | 1/20 | 0.39 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.39 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30637430 | 0.91 | SORD (0.47) | SORDACACBHSD17B10KDM4EALDH1A1 | |
| SCHEMBL30556652 | 0.84 | CYP2D6 (0.52) | SORDHSD17B10KDM4EALDH1A1TSHR | |
| SCHEMBL26646178 | 0.81 | SORD (0.52) | SORDHSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL26201769 | 0.79 | CYP2D6 (0.51) | EIF2AK4HSD17B10ALDH1A1TSHRHPGD | |
| SCHEMBL26047171 | 0.79 | SORD (0.40) | SORDHSD17B10KDM4EALDH1A1TSHR | |
| SCHEMBL20745960 | 0.79 | ACACB (0.41) | SORDACACBEIF2AK4HSD17B10ALDH1A1 | |
| SCHEMBL13806030 | 0.79 | SORD (0.55) | SORDHSD17B10KDM4EALDH1A1TSHR | |
| SCHEMBL7904079 | 0.79 | SORD (0.55) | SORDHSD17B10KDM4EALDH1A1TSHR | |
| SCHEMBL18228454 | 0.79 | SORD (0.55) | SORDHSD17B10KDM4EALDH1A1TSHR | |
| SCHEMBL12597157 | 0.77 | KDM4E (0.55) | SORDHSD17B10KDM4EALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023198209-A1 | KIF18A INHIBITOR AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2023-10-19 | — | — | WO | disclosed |