SCHEMBL26201806

SCHEMBL26201806

CO[C@@H]1[C@H](OP(=O)([O-])OC[C@H]2O[C@@H](n3cnc4c(=O)[nH]c(N)nc43)[C@H](O)[C@@H]2O)[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)OC[C@H]2O[C@@H](n3c[n+](C)c4c(=O)[nH]c(N)nc43)[C@H](O)[C@@H]2COC(F)(F)F)O[C@H]1n1cnc2c(N)ncnc21

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DCPS Q96C86 1/20 0.51
P2RY1 P47900 4/20 0.50
P2RY2 P41231 2/20 0.50
SRC P12931 1/20 0.50
P2RX1 P51575 1/20 0.50
P2RX3 P56373 1/20 0.50
P2RX4 Q99571 1/20 0.50
P2RX2 Q9UBL9 1/20 0.50
ALDH1A1 P00352 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
RNASEL Q05823 3/20 0.49
FUT5 Q11128 1/20 0.49
TGM2 P21980 1/20 0.49
GK P32189 1/20 0.49
MACROD2 A1Z1Q3 1/20 0.48
SIRT6 Q8N6T7 1/20 0.48
MACROD1 Q9BQ69 1/20 0.48
TRPM2 O94759 1/20 0.48
KRAS P01116 1/20 0.47
PARG Q86W56 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26631664 0.96 DCPS (0.49) DCPSP2RY1P2RY2SRCP2RX1
SCHEMBL26569204 0.95 DCPS (0.50) DCPSP2RY1P2RY2SRCP2RX1
SCHEMBL26201807 0.94 RNASEL (0.55) P2RY1P2RY2SRCP2RX1P2RX3
SCHEMBL26213547 0.93 P2RY1 (0.53) DCPSP2RY1P2RY2SRCP2RX1
SCHEMBL26622375 0.93 P2RY1 (0.53) DCPSP2RY1P2RY2SRCP2RX1
SCHEMBL26218376 0.93 P2RY1 (0.53) DCPSP2RY1P2RY2SRCP2RX1
SCHEMBL26201564 0.93 FUT5 (0.55) DCPSP2RY2P2RX3RNASELFUT5
SCHEMBL26212882 0.93 FUT5 (0.55) DCPSP2RY2P2RX3RNASELFUT5
SCHEMBL26201810 0.92 P2RY1 (0.51) DCPSP2RY1P2RY2SRCP2RX1
SCHEMBL26572570 0.92 P2RY1 (0.52) DCPSP2RY1P2RY2SRCP2RX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023159930-A1 COMPOUND FOR RNA CAPPING AND APPLICATION OF COMPOUND 广州市恒诺康医药科技有限公司 2023-08-31 WO disclosed