Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 4/20 | 0.37 |
| ▸ | CNR2 | P34972 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.35 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.35 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25030411 | 1.00 | SMYD3 (0.42) | SMYD3EPHX2DRD2HTR2ADRD3 | |
| SCHEMBL25029219 | 0.91 | SMYD3 (0.38) | SMYD3EPHX2DRD2HTR2ADRD3 | |
| SCHEMBL25030412 | 0.85 | EPHX2 (0.36) | SMYD3EPHX2SMN1; SMN2MAPTCNR1 | |
| SCHEMBL26201850 | 0.85 | EPHX2 (0.39) | SMYD3EPHX2DRD2HTR2ADRD3 | |
| SCHEMBL10132074 | 0.82 | SMN1; SMN2 (0.52) | SMYD3SMN1; SMN2MAPTCNR1CNR2 | |
| SCHEMBL26062909 | 0.80 | RAB9A (0.34) | SMYD3EPHX2L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL25029218 | 0.79 | CNR1 (0.33) | SMYD3EPHX2SMN1; SMN2MAPTCNR1 | |
| SCHEMBL26062862 | 0.78 | NPSR1 (0.40) | SMYD3EPHX2DRD2HTR2ADRD3 | |
| SCHEMBL25030885 | 0.78 | NPSR1 (0.40) | SMYD3EPHX2DRD2HTR2ADRD3 | |
| SCHEMBL26211095 | 0.78 | EPHX2 (0.36) | EPHX2MAPTCNR1CNR2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023161877-A1 | CYTOTOXICITY TARGETING CHIMERAS FOR INTEGRIN AVB6-EXPRESSING CELLS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-08-31 | — | — | WO | disclosed |