Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | CNR1 | P21554 | 4/20 | 0.45 |
| ▸ | CNR2 | P34972 | 4/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13708640 | 0.90 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1HPGDCNR1CNR2 | |
| SCHEMBL12094076 | 0.85 | RAB9A (0.48) | SMN1; SMN2MAPTNPSR1 | |
| SCHEMBL12094075 | 0.85 | NPSR1 (0.42) | SMN1; SMN2ALDH1A1CNR1CNR2MAPT | |
| SCHEMBL23157621 | 0.82 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1HPGDHDAC3HDAC1 | |
| SCHEMBL20927250 | 0.82 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1HPGDCNR1CNR2 | |
| SCHEMBL25030411 | 0.82 | SMYD3 (0.42) | SMN1; SMN2ALDH1A1HPGDCNR1CNR2 | |
| SCHEMBL26201847 | 0.82 | SMYD3 (0.42) | SMN1; SMN2ALDH1A1HPGDCNR1CNR2 | |
| SCHEMBL14163196 | 0.81 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1HPGDHDAC3HDAC1 | |
| SCHEMBL25030885 | 0.81 | NPSR1 (0.40) | SMN1; SMN2ALDH1A1HPGDCNR1CNR2 | |
| SCHEMBL26062862 | 0.81 | NPSR1 (0.40) | SMN1; SMN2ALDH1A1HPGDCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101186-B2 | Peptides that block the binding of IgG to FcRn | SYNTONIX PHARMACEUTICALS, INC. (US) | 2012-01-24 | — | — | US | disclosed |
| US-20070254831-A1 | PEPTIDES THAT BLOCK THE BINDING OF IgG to FcRn | BIOGEN HEMOPHILIA INC. | 2007-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070254831-A1 | PEPTIDES THAT BLOCK THE BINDING OF IgG to FcRn | FCGRT, FCGR3B, FCGR1A | SMN1; SMN2 4722/4885ALDH1A1 4835/4885HPGD 3932/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.