Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 5/20 | 0.36 |
| ▸ | CNR1 | P21554 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25029638 | 0.89 | MME (0.40) | DRD2HTR2ADRD3CNR2CNR1 | |
| SCHEMBL26201849 | 0.88 | EPHX2 (0.36) | EPHX2SMYD3DRD2HTR2ADRD3 | |
| SCHEMBL26201902 | 0.88 | CNR2 (0.44) | CNR2CNR1MAPTMEN1ALDH1A1 | |
| SCHEMBL25030878 | 0.88 | EPHX2 (0.36) | EPHX2SMYD3DRD2HTR2ADRD3 | |
| SCHEMBL25030401 | 0.87 | DRD2 (0.38) | SMYD3DRD2HTR2ADRD3L3MBTL1 | |
| SCHEMBL26058739 | 0.87 | USP2 (0.35) | EPHX2SMYD3DRD2HTR2ADRD3 | |
| SCHEMBL25030873 | 0.85 | MEN1 (0.42) | SMYD3CNR2CNR1MAPTSMN1; SMN2 | |
| SCHEMBL25030411 | 0.85 | SMYD3 (0.42) | EPHX2SMYD3DRD2HTR2ADRD3 | |
| SCHEMBL26201847 | 0.85 | SMYD3 (0.42) | EPHX2SMYD3DRD2HTR2ADRD3 | |
| SCHEMBL25030880 | 0.84 | CNR2 (0.39) | SMYD3CNR2CNR1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023161877-A1 | CYTOTOXICITY TARGETING CHIMERAS FOR INTEGRIN AVB6-EXPRESSING CELLS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-08-31 | — | — | WO | disclosed |