Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 5/20 | 0.35 |
| ▸ | CNR2 | P34972 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | SELL | P14151 | 1/20 | 0.32 |
| ▸ | SELP | P16109 | 1/20 | 0.32 |
| ▸ | SELE | P16581 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25030878 | 1.00 | EPHX2 (0.36) | EPHX2CNR1CNR2MAPTSMN1; SMN2 | |
| SCHEMBL26062908 | 0.89 | RXFP1 (0.33) | EPHX2CNR1CNR2MAPTSMN1; SMN2 | |
| SCHEMBL26201850 | 0.88 | EPHX2 (0.39) | EPHX2CNR1CNR2MAPTSMN1; SMN2 | |
| SCHEMBL25029638 | 0.88 | MME (0.40) | CNR1CNR2MAPTSMN1; SMN2NPC1 | |
| SCHEMBL25030412 | 0.88 | EPHX2 (0.36) | EPHX2CNR1CNR2MAPTSMN1; SMN2 | |
| SCHEMBL25028347 | 0.86 | POLB (0.32) | EPHX2CNR1CNR2MAPTSMN1; SMN2 | |
| SCHEMBL25030380 | 0.85 | DRD2 (0.33) | CNR1CNR2MAPTSMN1; SMN2SMYD3 | |
| SCHEMBL25029992 | 0.85 | DRD2 (0.33) | CNR1CNR2MAPTSMN1; SMN2SMYD3 | |
| SCHEMBL25029513 | 0.85 | DRD2 (0.33) | CNR1CNR2MAPTSMN1; SMN2SMYD3 | |
| SCHEMBL26201902 | 0.84 | CNR2 (0.44) | CNR1CNR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023161877-A1 | CYTOTOXICITY TARGETING CHIMERAS FOR INTEGRIN AVB6-EXPRESSING CELLS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-08-31 | — | — | WO | disclosed |