Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 13/20 | 0.44 |
| ▸ | CNR1 | P21554 | 9/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.41 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.41 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25030880 | 0.88 | CNR2 (0.39) | CNR2CNR1MEN1ALDH1A1MAPT | |
| SCHEMBL26201850 | 0.88 | EPHX2 (0.39) | CNR2CNR1MEN1ALDH1A1MAPT | |
| SCHEMBL26201903 | 0.87 | CASP2 (0.38) | CNR2CNR1MEN1ALDH1A1MAPT | |
| SCHEMBL25029638 | 0.85 | MME (0.40) | CNR2CNR1MAPT | |
| SCHEMBL26201849 | 0.84 | EPHX2 (0.36) | CNR2CNR1MAPT | |
| SCHEMBL25030878 | 0.84 | EPHX2 (0.36) | CNR2CNR1MAPT | |
| SCHEMBL25030414 | 0.83 | CNR2 (0.41) | CNR2CNR1MEN1ALDH1A1MAPT | |
| SCHEMBL26058701 | 0.82 | SMN1; SMN2 (0.39) | CNR2CNR1ALDH1A1HPGDKMT2A | |
| SCHEMBL25030873 | 0.81 | MEN1 (0.42) | CNR2CNR1MEN1MAPTKMT2A | |
| SCHEMBL25030401 | 0.81 | DRD2 (0.38) | CNR2CNR1MEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023161879-A1 | CYTOTOXICITY TARGETING CHIMERAS FOR FIBROBLAST ACTIVATION PROTEIN-EXPRESSING CELLS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-08-31 | — | — | WO | disclosed |
| WO-2023161877-A1 | CYTOTOXICITY TARGETING CHIMERAS FOR INTEGRIN AVB6-EXPRESSING CELLS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-08-31 | — | — | WO | disclosed |