SCHEMBL26201875

SCHEMBL26201875

CCCCOC[C@H]1[C@@H](O)[C@H](n2c[n+](C)c3c(=O)[nH]c(N)nc32)O[C@@H]1COP(=O)(O)OP(=O)(O)OP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](OC)[C@@H]1OP(=O)(O)OC[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)[C@H](O)[C@@H]1O

nearest known ligand 0.59

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
RNASEL Q05823 7/20 0.59
P2RY2 P41231 4/20 0.58
P2RY4 P51582 1/20 0.50
P2RY6 Q15077 1/20 0.50
P2RY1 P47900 3/20 0.47
SRC P12931 1/20 0.47
P2RX1 P51575 1/20 0.47
P2RX3 P56373 1/20 0.47
P2RX4 Q99571 1/20 0.47
P2RX2 Q9UBL9 1/20 0.47
ALDH1A1 P00352 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26213916 0.97 RNASEL (0.60) RNASELP2RY2P2RY4P2RY6P2RY1
SCHEMBL26214068 0.97 RNASEL (0.58) RNASELP2RY2P2RY4P2RY6P2RY1
SCHEMBL26201803 0.96 RNASEL (0.60) RNASELP2RY2P2RY4P2RY6P2RY1
SCHEMBL26622397 0.96 RNASEL (0.60) RNASELP2RY2P2RY4P2RY6P2RY1
SCHEMBL26201872 0.94 P2RY2 (0.56) RNASELP2RY2P2RY4P2RY6P2RY1
SCHEMBL26213497 0.94 RNASEL (0.63) RNASELP2RY2P2RY4P2RY6P2RY1
SCHEMBL26584183 0.94 RNASEL (0.53) RNASELP2RY2P2RY1SRCP2RX1
SCHEMBL26622378 0.94 RNASEL (0.63) RNASELP2RY2P2RY4P2RY6P2RY1
SCHEMBL26201988 0.93 P2RY2 (0.58) RNASELP2RY2P2RY4P2RY6P2RY1
SCHEMBL25584001 0.93 RNASEL (0.67) RNASELP2RY2P2RY4P2RY6P2RY1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230340009-A1 COMPOUNDS FOR RNA CAPPING AND USES THEREOF GUANGZHOU HENOVCOM BIOSCIENCE CO., LTD. (CN) 2023-10-26 US disclosed
WO-2023159930-A1 COMPOUND FOR RNA CAPPING AND APPLICATION OF COMPOUND 广州市恒诺康医药科技有限公司 2023-08-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230340009-A1 COMPOUNDS FOR RNA CAPPING AND USES THEREOF RNGTT, RNMT, NSUN2 RNASEL 72/4885P2RY2 4360/4885P2RY4 4359/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.