Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 3/20 | 0.35 |
| ▸ | HTR2A | P28223 | 3/20 | 0.35 |
| ▸ | DRD3 | P35462 | 3/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26062908 | 0.89 | RXFP1 (0.33) | POLBNPC1RAB9ATSHREPHX2 | |
| SCHEMBL25028605 | 0.89 | CNR1 (0.39) | POLBNPC1RAB9ADRD2HTR2A | |
| SCHEMBL25029638 | 0.89 | MME (0.40) | POLBNPC1RAB9ADRD2HTR2A | |
| SCHEMBL26201979 | 0.88 | RAB9A (0.36) | POLBNPC1RAB9AKDM4EEPHX2 | |
| SCHEMBL25027795 | 0.88 | KMT2A (0.37) | POLBNPC1RAB9AEPHX2MAPT | |
| SCHEMBL25030873 | 0.87 | MEN1 (0.42) | POLBNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL26058739 | 0.86 | USP2 (0.35) | POLBNPC1RAB9AKDM4EDRD2 | |
| SCHEMBL25028347 | 0.86 | POLB (0.32) | POLBNPC1RAB9AEPHX2SMN1; SMN2 | |
| SCHEMBL26201903 | 0.85 | CASP2 (0.38) | TSHREPHX2MAPTNPSR1ALDH1A1 | |
| SCHEMBL26062957 | 0.84 | POLB (0.39) | POLBNPC1RAB9ADRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023161877-A1 | CYTOTOXICITY TARGETING CHIMERAS FOR INTEGRIN AVB6-EXPRESSING CELLS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-08-31 | — | — | WO | disclosed |