Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 3/20 | 0.32 |
| ▸ | CNR2 | P34972 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25028347 | 0.89 | POLB (0.32) | SMYD3POLBCNR1CNR2NPC1 | |
| SCHEMBL26201850 | 0.87 | EPHX2 (0.39) | SMYD3L3MBTL1DRD2HTR2ADRD3 | |
| SCHEMBL26201907 | 0.86 | POLB (0.40) | DRD2HTR2ADRD3POLBCNR1 | |
| SCHEMBL26062908 | 0.85 | RXFP1 (0.33) | SMYD3POLBCNR1CNR2NPC1 | |
| SCHEMBL25028605 | 0.85 | CNR1 (0.39) | SMYD3DRD2HTR2ADRD3POLB | |
| SCHEMBL25030873 | 0.85 | MEN1 (0.42) | SMYD3POLBCNR1CNR2NPC1 | |
| SCHEMBL25027795 | 0.84 | KMT2A (0.37) | SMYD3POLBCNR1CNR2NPC1 | |
| SCHEMBL26201979 | 0.84 | RAB9A (0.36) | SMYD3POLBCNR1CNR2NPC1 | |
| SCHEMBL26058737 | 0.83 | EPHX2 (0.38) | DRD2HTR2ADRD3EPHX2MEN1 | |
| SCHEMBL26201903 | 0.83 | CASP2 (0.38) | SMYD3CNR1CNR2EPHX2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023161874-A1 | CYTOTOXICITY TARGETING CHIMERAS FOR C-C CHEMOKINE RECEPTOR 2-EXPRESSING CELLS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-08-31 | — | — | WO | disclosed |