Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NCK1 | P16333 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26205353 | 0.78 | CYP1A2 (0.42) | ALDH1A1KDM4EGAALMNAHPGD | |
| SCHEMBL11495194 | 0.77 | CYP1A2 (0.46) | ALDH1A1KDM4EGAALMNAHPGD | |
| SCHEMBL27908985 | 0.76 | CYP1A2 (0.41) | ALDH1A1KDM4EGAALMNAHPGD | |
| SCHEMBL25696104 | 0.73 | ALDH1A1 (0.43) | ALDH1A1KDM4EGAALMNAHPGD | |
| SCHEMBL11801599 | 0.72 | ALDH1A1 (0.44) | ALDH1A1KDM4EGAAHPGDHSD17B10 | |
| SCHEMBL30032994 | 0.72 | ALDH1A1 (0.44) | ALDH1A1KDM4EGAAHPGDHSD17B10 | |
| SCHEMBL8150504 | 0.72 | ALDH1A1 (0.46) | ALDH1A1KDM4EGAALMNAHPGD | |
| SCHEMBL27590342 | 0.72 | CYP2A6 (0.42) | ALDH1A1KDM4EGAALMNAHPGD | |
| SCHEMBL32664327 | 0.72 | CYP1A2 (0.50) | ALDH1A1KDM4EGAALMNAHPGD | |
| SCHEMBL18965686 | 0.71 | ALDH1A1 (0.59) | ALDH1A1KDM4EGAALMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230279025-A1 | KRAS G12D INHIBITORS | ARRAY BIOPHARMA INC. | 2023-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230279025-A1 | KRAS G12D INHIBITORS | KRAS, NRAS, HRAS | ALDH1A1 2943/4885KDM4E 3425/4885GAA 1310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.