Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17323165 | 0.79 | ALDH1A1 (0.56) | ALDH1A1KDM4EHSD17B10LMNATDP1 | |
| SCHEMBL8150490 | 0.78 | ALDH1A1 (0.47) | ALDH1A1KDM4EHSD17B10LMNAGAA | |
| SCHEMBL8154443 | 0.76 | ALDH1A1 (0.46) | ALDH1A1KDM4EHSD17B10LMNAGAA | |
| SCHEMBL1429141 | 0.72 | ALDH1A1 (0.50) | ALDH1A1KDM4EHSD17B10LMNAGAA | |
| SCHEMBL25625349 | 0.72 | CYP2A6 (0.52) | ALDH1A1KDM4EHSD17B10LMNAGAA | |
| SCHEMBL16153617 | 0.72 | ALDH1A1 (0.55) | ALDH1A1KDM4EHSD17B10LMNAGAA | |
| SCHEMBL26205352 | 0.72 | ALDH1A1 (0.46) | ALDH1A1KDM4EHSD17B10LMNAGAA | |
| SCHEMBL9485022 | 0.72 | ALDH1A1 (0.52) | ALDH1A1KDM4EHSD17B10TDP1ALOX15 | |
| SCHEMBL7714126 | 0.72 | KIF11 (0.36) | ALDH1A1KDM4EHSD17B10MAPTMEN1 | |
| SCHEMBL32664327 | 0.72 | CYP1A2 (0.50) | ALDH1A1KDM4EHSD17B10LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116399-A1 | Inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. | 2004-06-17 | — | — | US | disclosed |
| US-20040116399-A1 | Inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. | 2004-06-17 | — | — | US | disclosed |