Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26205652 | 0.89 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL26205646 | 0.88 | PTGER1 (0.33) | — | |
| SCHEMBL26205632 | 0.82 | SMN1; SMN2 (0.36) | — | |
| SCHEMBL26205644 | 0.81 | FFAR4 (0.33) | FFAR4 | |
| SCHEMBL23833022 | 0.79 | PKM (0.30) | PKMMAP2K1 | |
| SCHEMBL22526455 | 0.78 | AAK1 (0.48) | — | |
| SCHEMBL23833020 | 0.78 | AAK1 (0.48) | — | |
| SCHEMBL30169280 | 0.78 | AAK1 (0.48) | — | |
| SCHEMBL26206437 | 0.77 | F13A1 (0.37) | FFAR1FFAR4 | |
| SCHEMBL26205638 | 0.77 | AAK1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11746120-B2 | Stat degraders and uses thereof | KYMERA THERAPEUTICS, INC. (US) | 2023-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11746120-B2 | Stat degraders and uses thereof | STAT4, STAT1, STAT3 | PKM 2073/4885FFAR1 4114/4885FFAR4 3503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.