SCHEMBL26205644

SCHEMBL26205644

C[C@@H](CCC(N)=O)COc1cc(F)cc(Br)c1

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ FFAR4 Q5NUL3 1/20 0.33
▸ GPR88 Q9GZN0 1/20 0.32
▸ ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26205640 0.86 ALDH1A1 (0.34) GPR88ALDH1A1
SCHEMBL26205636 0.84 CYP1A2 (0.35) GPR88
SCHEMBL26205653 0.81 PKM (0.33) FFAR4
SCHEMBL26205633 0.80 HSD17B10 (0.48) ALDH1A1
SCHEMBL26205631 0.79 MAPT (0.44) FFAR4GPR88ALDH1A1
SCHEMBL17647713 0.79 FFAR4 (0.32) FFAR4GPR88
SCHEMBL26205643 0.78 GPR88 (0.35) GPR88
SCHEMBL22526339 0.77 AAK1 (0.47) —
SCHEMBL30169238 0.77 AAK1 (0.47) —
SCHEMBL26206484 0.77 FFAR4 (0.37) FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11746120-B2 Stat degraders and uses thereof KYMERA THERAPEUTICS, INC. (US) 2023-09-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11746120-B2 Stat degraders and uses thereof STAT4, STAT1, STAT3 FFAR4 3503/4885GPR88 3720/4885ALDH1A1 2465/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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