Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 2/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.36 |
| ▸ | CSF3R | Q99062 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | FOS | P01100 | 2/20 | 0.34 |
| ▸ | JUN | P05412 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26205873 | 0.90 | MAPT (0.37) | PTGER1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL27015304 | 0.90 | PTGER1 (0.33) | PTGER1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL26206383 | 0.87 | FOS (0.36) | PTGER1PTGER4PTGER3PTGER2CSF3R | |
| SCHEMBL26206390 | 0.84 | LTB4R (0.40) | PTGER1PTGER4PTGER3PTGER2CSF3R | |
| SCHEMBL26206385 | 0.83 | FOS (0.36) | PTGER1PTGER4PTGER3PTGER2CSF3R | |
| SCHEMBL26206433 | 0.83 | F13A1 (0.37) | PTGER1PTGER4PTGER3PTGER2CSF3R | |
| SCHEMBL26206391 | 0.81 | LTB4R (0.44) | PTGER1PTGER4PTGER3PTGER2FOS | |
| SCHEMBL27015526 | 0.81 | LTB4R (0.44) | PTGER1PTGER4PTGER3PTGER2FOS | |
| SCHEMBL23832934 | 0.80 | AAK1 (0.42) | PTGER1PTGER4PTGER3PTGER2TSHR | |
| SCHEMBL22525537 | 0.80 | AAK1 (0.42) | PTGER1PTGER4PTGER3PTGER2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240016942-A1 | STAT DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2024-01-18 | — | — | US | disclosed |
| US-11746120-B2 | Stat degraders and uses thereof | KYMERA THERAPEUTICS, INC. (US) | 2023-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11746120-B2 | Stat degraders and uses thereof | STAT4, STAT1, STAT3 | PTGER1 2776/4885PTGER4 2085/4885PTGER3 2989/4885 |
| US-20240016942-A1 | STAT DEGRADERS AND USES THEREOF | STAT4, STAT1, STAT3 | PTGER1 2776/4885PTGER4 2085/4885PTGER3 2989/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.