SCHEMBL27015304

SCHEMBL27015304

Cc1cc(CCCCO)c(Cl)c(OC[C@@H](C)CCC(N)=O)c1

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ PTGER1 P34995 1/20 0.33
▸ GCK P35557 1/20 0.32
▸ GAA P10253 1/20 0.32
▸ KDM4E B2RXH2 1/20 0.30
▸ ALDH1A1 P00352 1/20 0.30
▸ HPGD P15428 1/20 0.30
▸ HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26206444 0.90 PTGER1 (0.36) PTGER1GAAKDM4EALDH1A1HPGD
SCHEMBL26205873 0.87 MAPT (0.37) PTGER1GAAKDM4EALDH1A1HPGD
SCHEMBL27015244 0.83 ADRB2 (0.37) —
SCHEMBL23833042 0.82 — —
SCHEMBL23833040 0.81 AAK1 (0.42) PTGER1ALDH1A1HPGD
SCHEMBL23833159 0.81 AAK1 (0.42) PTGER1ALDH1A1HPGD
SCHEMBL27015257 0.80 ADRB2 (0.39) —
SCHEMBL27015309 0.79 PTGER1 (0.34) PTGER1GAAKDM4EALDH1A1
SCHEMBL22526501 0.78 ALDH1A1 (0.33) KDM4EALDH1A1
SCHEMBL26206385 0.78 FOS (0.36) PTGER1KDM4EALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240016942-A1 STAT DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2024-01-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240016942-A1 STAT DEGRADERS AND USES THEREOF STAT4, STAT1, STAT3 PTGER1 2776/4885GCK 2181/4885GAA 312/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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