SCHEMBL26207381

SCHEMBL26207381

CO[C@@H]1[C@H](OP(=O)(O)OC[C@H]2O[C@@H](n3cnc4c(=O)[nH]c(N)nc43)[C@H](O)[C@@H]2O)[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)OC[C@H]2O[C@@H](n3c[n+](C)c4c(=O)[nH]c(N)nc43)[C@H](O)[C@@H]2COCc2ccccc2)O[C@H]1n1cnc2c(N)ncnc21

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
RNASEL Q05823 8/20 0.52
P2RY2 P41231 3/20 0.50
P2RY12 Q9H244 1/20 0.50
P2RY1 P47900 3/20 0.49
SRC P12931 1/20 0.49
P2RX1 P51575 1/20 0.49
P2RX3 P56373 1/20 0.49
P2RX4 Q99571 1/20 0.49
P2RX2 Q9UBL9 1/20 0.49
ALDH1A1 P00352 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
FUT5 Q11128 1/20 0.49
TGM2 P21980 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26622038 0.96 FUT5 (0.52) RNASELP2RY2FUT5TGM2
SCHEMBL26201797 0.94 RNASEL (0.58) RNASELP2RY2P2RY12P2RY1SRC
SCHEMBL26622391 0.92 RNASEL (0.55) RNASELP2RY2P2RY1SRCP2RX1
SCHEMBL26209313 0.92 RNASEL (0.57) RNASELP2RY2P2RY1SRCP2RX1
SCHEMBL26207269 0.92 RNASEL (0.57) RNASELP2RY2P2RY1SRCP2RX1
SCHEMBL25583996 0.92 RNASEL (0.61) RNASELP2RY2P2RY1SRCP2RX1
SCHEMBL25896437 0.92 RNASEL (0.61) RNASELP2RY2P2RY1SRCP2RX1
SCHEMBL25895037 0.92 RNASEL (0.61) RNASELP2RY2P2RY1SRCP2RX1
SCHEMBL27410758 0.92 RNASEL (0.61) RNASELP2RY2P2RY1SRCP2RX1
SCHEMBL26331783 0.92 RNASEL (0.61) RNASELP2RY2P2RY1SRCP2RX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4261217-A1 COMPOUND FOR RNA CAPPING AND APPLICATION OF COMPOUND Guangzhou Henovcom Bioscience Co., Ltd. (CN) 2023-10-18 EP disclosed
WO-2023159930-A1 COMPOUND FOR RNA CAPPING AND APPLICATION OF COMPOUND 广州市恒诺康医药科技有限公司 2023-08-31 WO disclosed