Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 4/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.44 |
| ▸ | PSMB8 | P28062 | 3/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 2/20 | 0.42 |
| ▸ | MMP8 | P22894 | 2/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | CPA1 | P15085 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26211712 | 0.93 | OPRD1 (0.45) | OPRD1CTSSCTSKPSMB5PSMB8 | |
| SCHEMBL26211704 | 0.79 | OPRD1 (0.45) | OPRD1CTSSCTSKOPRM1 | |
| SCHEMBL26211758 | 0.79 | OPRD1 (0.49) | OPRD1OPRM1 | |
| SCHEMBL25475251 | 0.74 | OPRD1 (0.52) | OPRD1CTSSCTSKOPRM1OPRK1 | |
| SCHEMBL25503977 | 0.72 | PSMB5 (0.48) | OPRD1CTSSPSMB5MMP9MMP8 | |
| SCHEMBL24765226 | 0.70 | CTSB (0.57) | OPRD1MMP9OPRM1OPRK1CTSB | |
| SCHEMBL25475427 | 0.69 | CTSB (0.53) | OPRD1PSMB5PSMB8MMP8OPRM1 | |
| SCHEMBL24823298 | 0.69 | PSMB5 (0.50) | OPRD1CTSSPSMB5OPRM1OPRK1 | |
| SCHEMBL24764553 | 0.69 | CTSB (0.54) | OPRD1CTSSMMP9OPRM1OPRK1 | |
| SCHEMBL24765225 | 0.69 | CTSB (0.54) | OPRD1CTSSMMP9OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11746126-B2 | Bicyclic peptide ligands with detectable moieties and uses thereof | Bicyclerd Limited (GB) | 2023-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11746126-B2 | Bicyclic peptide ligands with detectable moieties and uses thereof | VIP, NGLY1, GRPR | OPRD1 3256/4885CTSS 1469/4885CTSK 575/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.