Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26213325 | 0.84 | DRD2 (0.42) | KMT2AKDM4EALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL26213316 | 0.82 | KDM4E (0.45) | KMT2AKDM4EALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL26213303 | 0.80 | KMT2A (0.56) | KMT2AKDM4EALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL26213311 | 0.78 | TUBB4A (0.44) | KMT2AKDM4EALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL26213291 | 0.76 | KDM4E (0.49) | KDM4EALDH1A1SMN1; SMN2HPGDLMNA | |
| SCHEMBL2735787 | 0.76 | KMT2A (0.55) | KMT2AKDM4EALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL26213330 | 0.74 | GABRA1 (0.43) | KMT2AKDM4EALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL24196813 | 0.73 | MAP2 (0.44) | KMT2AKDM4EALDH1A1MEN1LMNA | |
| SCHEMBL30270459 | 0.73 | MAP2 (0.44) | KMT2AKDM4EALDH1A1MEN1LMNA | |
| SCHEMBL30270439 | 0.73 | GABRA1 (0.41) | KDM4ESMN1; SMN2LMNAGABRA1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4175718-B1 | INDOLE DERIVATIVES AND USES THEREOF FOR TREATING A CANCER | UNIV CLAUDE BERNARD LYON (FR) | 2024-10-02 | — | — | EP | disclosed |
| CN-115843271-A | Indole derivatives and their use for the treatment of cancer | 克洛德贝纳尔-里昂第一大学 | 2023-03-24 | — | — | CN | disclosed |