Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | KIT | P10721 | 6/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | BRAF | P15056 | 6/20 | 0.55 |
| ▸ | CSF1R | P07333 | 1/20 | 0.54 |
| ▸ | EGFR | P00533 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | RET | P07949 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | CLK1 | P49759 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26215337 | 0.84 | EGFR (0.64) | ATMKITMAPTBRAFEGFR | |
| SCHEMBL26215628 | 0.83 | HTT (0.58) | ATMKITMAPTKMT2ANPSR1 | |
| SCHEMBL26215023 | 0.83 | EGFR (0.64) | ATMKITMAPTBRAFCSF1R | |
| SCHEMBL1420251 | 0.81 | EPHA2 (0.62) | ATMKITMAPTBRAFCSF1R | |
| SCHEMBL26215982 | 0.79 | MAPT (0.52) | ATMMAPTBRAFEGFRKMT2A | |
| SCHEMBL26214307 | 0.79 | EPHA2 (0.84) | ATMKITMAPTCSF1RKMT2A | |
| SCHEMBL31276009 | 0.78 | KIT (0.59) | KITBRAFEGFR | |
| SCHEMBL29562470 | 0.78 | BRAF (0.82) | KITBRAFCSF1REGFRRET | |
| SCHEMBL6184307 | 0.78 | BRAF (0.82) | KITBRAFCSF1REGFRRET | |
| SCHEMBL14318406 | 0.77 | KIT (0.77) | KITBRAFCSF1REGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023168107-A2 | COMPOUNDS AND COMPOSITIONS FOR ANITMALARIAL THERAPEUTIC AND PROPHYLACTIC USE | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) | 2023-09-07 | — | — | WO | disclosed |